Assessing the impact of COVID-19 on sleep and cognitive health
Official title: Predictors of Post-COVID Clinical and Cognitive Consequences
Run by VA Office of Research and Development · NCT06291870 · Data updated 2026-11-12
This study is trying to see how COVID-19 affects sleep and thinking in people who have recovered from the virus, to better understand long-term health issues they might face.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 1 site (Detroit, Michigan) |
| Status | Recruiting |
| Started | January 19, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | January 23, 2026 |
| Trial ID | NCT06291870 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 18 and older with a prior diagnosis of COVID-19, particularly those with obstructive sleep apnea.
✕Probably not a fit
Patients who are unable to provide consent, exhibit active suicidal symptoms, or are pregnant will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to systematically evaluate the relationship between sleep disturbances, obstructive sleep apnea, and post-acute sequelae of SARS-CoV-2 infection (PASC) in individuals who have recovered from COVID-19. It will collect data on sleep quality, cognitive function, and fatigue symptoms to understand how these factors may influence long-term health outcomes. The study will also explore the role of inflammatory biomarkers during acute COVID-19 infection in predicting the severity and duration of PASC. This pilot study serves as a foundation for future research on the connections between long-COVID and sleep-related issues.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for post-COVID conditions, enhancing quality of life for affected patients.
How similar studies have gone: While this study explores novel connections between COVID-19 and sleep disturbances, similar studies have indicated the importance of sleep quality in overall health outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All individuals 18 years or older, with prior history of COVID-19 infection diagnosis * Both genders including all racial and ethnic groups * Patients with OSA (apnea hypopnea index of 5/hour on polysomnography) with history of COVID-19 infection will be eligible with prior history of COVID-19 infection and without COVID-19 for Aim 2 Exclusion Criteria: * Inability to give consent * Active suicidal symptoms * Children of all ages * Pregnant women
Where it's running
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John D. Dingell VA Medical Center, Detroit, MI
Detroit, Michigan, United States Recruiting
Study contacts
- Principal investigator: Susmita Chowdhuri, MD MS — John D. Dingell VA Medical Center, Detroit, MI
- Study coordinator: Ruchi Rastogi, MS
- Email: ruchi.rastogi@va.gov
- Phone: (313) 576-4464
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography
Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.
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Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea
This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.
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Functional capacity and muscle function in adults with obstructive sleep apnea
This study tests how obstructive sleep apnea affects respiratory and peripheral muscle strength, endurance, and upper‑extremity function compared with healthy adults.
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Transcutaneous Electrical Stimulation for Obstructive Sleep Apnea
This study tests whether applying gentle electrical stimulation to the throat muscles at night can reduce sleep apnea severity in adults with obstructive sleep apnea.
-
Physical activity habits and sleep/ breathing in obstructive sleep apnea
This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.
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CES-EES score and a wearable ring for diagnosing obstructive sleep apnea
This study tests whether the CES-EES clinical score and the Belun Ring wearable can accurately diagnose obstructive sleep apnea without in-lab polysomnography in adults referred for suspected OSA.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.