Assessing the effects of cannabis on driving performance
High Confusion: Evaluating Effects of Popular Cannabis Isolates on Driving Performance
This study tests how different types of cannabis can affect driving skills to help understand the safety of using cannabis while driving.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 5 (estimated) |
| Ages | 18 Years to 49 Years |
| Sex | All |
| Sponsor | University of Wisconsin, Madison Academic / other |
| Locations | 1 site (Madison, Wisconsin) |
| Trial ID | NCT06236815 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility of administering Delta-9-THC and Delta-8-THC isolates to understand their impact on driving performance and cognitive impairment. Participants will receive standardized doses of these cannabinoids, and their driving abilities will be assessed using established impairment detection methods. The study aims to generate data that can inform future regulations and safety measures regarding cannabis use and driving. By comparing the effects of THC isolates to a placebo, the research seeks to clarify the relationship between cannabis consumption and driving impairment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 49 who have used cannabis recently and possess a valid driver's license.
Not a fit: Patients with a history of serious adverse reactions to cannabis or those with substance use disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide critical insights into the safety of cannabis use while driving, potentially influencing public health policies.
How similar studies have performed: While there have been studies on cannabis and driving, this approach of using standardized dosing and impairment detection methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 18 years of age, no older than 49 years of age * Recent cannabis use (within past two years) * Good mental health as determined by self-reported responses to the Psychopathology Screener * Absence of any major medical, cardiovascular, endocrine, and neurological condition as determined by self-reported responses to the Medical History Screener * In possession of a valid drivers' license with at least two years of driving experience * English-speaking (able to provide consent and complete questionnaires) * Written Informed Consent Exclusion Criteria: * Any serious prior adverse response to cannabis * History of or current substance use disorder as determined by self-reported responses to the Internalizing, Externalizing, and Substance Use Disorder Screener * Pregnancy or lactation (pregnancy test, if needed) * Use of medications that may impact driving ability (e.g., mood stabilizers, sedatives)
Where this trial is running
Madison, Wisconsin
- University of Wisconsin — Madison, Wisconsin, United States (Recruiting)
Study contacts
- Principal investigator: Heather Barkholtz, PhD — University of Wisconsin, Madison
- Study coordinator: Heather Barkholtz, PhD
- Email: hbarkholtz@wisc.edu
- Phone: 608-890-1967
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.