Assessing risks and outcomes in patients with mitral regurgitation

MItral Regurgitation Risk Assessment and CLinical modElling (MIRACLE Study)

Observational Sun Yat-sen University · NCT06876883

This study looks at patients with moderate to severe mitral regurgitation to see what factors might affect their health outcomes and help doctors make better treatment decisions.

Quick facts

Study typeObservational
Enrollment2000 (estimated)
Ages18 Years and up
SexAll
SponsorSun Yat-sen University Academic / other
Locations1 site (Guangzhou, Guangdong)
Trial IDNCT06876883 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients diagnosed with moderate to severe mitral regurgitation (MR) during hospitalization. It aims to identify prognostic risk factors associated with MR and develop a clinical model to aid in decision-making for treatment. By analyzing data from a prospective cohort, the study seeks to enhance understanding of mortality and heart failure hospitalization risks in MR patients. The findings could potentially inform better management strategies for individuals suffering from this condition.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old diagnosed with moderate to severe mitral regurgitation during hospitalization.

Not a fit: Patients who are unable to provide written consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved risk assessment and management strategies for patients with mitral regurgitation.

How similar studies have performed: While there have been studies on mitral regurgitation, this specific approach to risk assessment and clinical modeling is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with ≥ moderate mitral regurgitation during hospitalization.
* Aged over 18 yrs.

Exclusion Criteria:

* Patients unable to provide written consent.

Where this trial is running

Guangzhou, Guangdong

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Mitral InsufficiencyMitral Regurgitationmitral regurgitationall-cause mortalityclinical modellingcardiovascular mortalityheart failure hospitalization
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.