Clinical trial No longer in our active list Observational Ages 15 to 50

Assessing retinal changes in patients with inflammatory bowel diseases

Official title: Optical Coherence Tomography Angiography Assessment of Retinal Lesions in Inflammatory Bowel Diseases

Run by Tanta University · NCT04601805 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study looks at eye changes in people with inflammatory bowel diseases to see how their condition might affect their vision.

Quick facts

Study typeObservational
Ages15 Years to 50 Years
SexAll
Enrollment30 (estimated)
SponsorTanta University
Academic / other
Locations1 site (Tanta, El-Garbeia)
Trial IDNCT04601805 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with Crohn's disease or ulcerative colitis, either newly diagnosed or with chronic disease currently undergoing treatment.

Probably not a fit

Patients who have undergone recent ophthalmological surgery or have significant refractive errors or retinal diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to document vascular changes in the posterior segment of patients suffering from inflammatory bowel diseases (IBD) using optical coherence tomography angiography (OCTA). A total of 30 patients with IBD will be recruited from the tropical department of Tanta University Hospital. The study will involve comprehensive ophthalmologic examinations, including OCTA and fundus photography, to evaluate the retinal capillary plexus and choriocapillaries. Patient demographics, symptoms, and treatment history will also be recorded to correlate findings with disease severity.

Why it matters

Potential benefit: If successful, this study could enhance understanding of retinal complications in IBD, leading to better management and treatment strategies for affected patients.

How similar studies have gone: While this approach is relatively novel in the context of IBD, similar studies have shown promise in assessing retinal changes in other systemic diseases.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with Crohn's disease and ulcerative colitis either newly diagnosed or suffering from chronic disease on treatment will be included

Exclusion Criteria:

* Recent ophthalmological surgery.

  * Low quality ophthalmological exams.
  * Refractive errors greater than + 3 or - 3 spherical.
  * Retinopathies such as diabetic retinopathy.
  * Any type of retinal degenerations or retinal dystrophy.

Where it's running

  • Tanta University Hospital
    Tanta, El-Garbeia, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.