Assessing retinal changes in patients with inflammatory bowel diseases
Official title: Optical Coherence Tomography Angiography Assessment of Retinal Lesions in Inflammatory Bowel Diseases
Run by Tanta University · NCT04601805 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study looks at eye changes in people with inflammatory bowel diseases to see how their condition might affect their vision.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 15 Years to 50 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, El-Garbeia) |
| Trial ID | NCT04601805 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with Crohn's disease or ulcerative colitis, either newly diagnosed or with chronic disease currently undergoing treatment.
✕Probably not a fit
Patients who have undergone recent ophthalmological surgery or have significant refractive errors or retinal diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to document vascular changes in the posterior segment of patients suffering from inflammatory bowel diseases (IBD) using optical coherence tomography angiography (OCTA). A total of 30 patients with IBD will be recruited from the tropical department of Tanta University Hospital. The study will involve comprehensive ophthalmologic examinations, including OCTA and fundus photography, to evaluate the retinal capillary plexus and choriocapillaries. Patient demographics, symptoms, and treatment history will also be recorded to correlate findings with disease severity.
Why it matters
Potential benefit: If successful, this study could enhance understanding of retinal complications in IBD, leading to better management and treatment strategies for affected patients.
How similar studies have gone: While this approach is relatively novel in the context of IBD, similar studies have shown promise in assessing retinal changes in other systemic diseases.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with Crohn's disease and ulcerative colitis either newly diagnosed or suffering from chronic disease on treatment will be included Exclusion Criteria: * Recent ophthalmological surgery. * Low quality ophthalmological exams. * Refractive errors greater than + 3 or - 3 spherical. * Retinopathies such as diabetic retinopathy. * Any type of retinal degenerations or retinal dystrophy.
Where it's running
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Tanta University Hospital
Tanta, El-Garbeia, Egypt Recruiting
Study contacts
- Study coordinator: Dina SM Tadros, MD
- Email: dinasabry@rocketmail.com
- Phone: 00201224093354
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Long-Term Guselkumab Use in Adults with Inflammatory Bowel Disease
This study looks at how long adults with Crohn's disease or ulcerative colitis stay on guselkumab in real-world care.
-
Intestinal ultrasound-guided management for inflammatory bowel disease
This study tests if adding point-of-care intestinal ultrasound at every visit changes treatment decisions for adults with Crohn’s disease or ulcerative colitis undergoing disease assessment.
-
Resting energy use in kids with inflammatory bowel disease
This multicenter study will test the resting energy expenditure of children aged 6–17 with new IBD diagnoses to see how it relates to disease activity and treatment.
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Active video education by disease subtype to improve bowel prep before colonoscopy
We’re testing whether adding subtype-specific video education to standard prep improves bowel cleanliness in adults with IBD undergoing colonoscopy.
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Intestinal ultrasound to predict relapse in Crohn's disease patients in deep remission.
This project will try to see if a noninvasive transabdominal ultrasound can predict relapses in adults with Crohn's disease who are currently in deep remission.
-
Ath-063: Testing a new treatment for moderately to severely active ulcerative colitis in patients who have tried other biologics
This study tests ATH-063 to see if it helps people with moderate to severe ulcerative colitis who did not respond to or relapsed after prior biologic therapy.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.