Assessing quality of life in patients with hypertrophic cardiomyopathy in Japan

Health-Related Quality of Life in Patients With Hypertrophic Cardiomyopathy in Japan

Observational Bristol-Myers Squibb · NCT06181617

This study is trying to see how living with hypertrophic cardiomyopathy affects the daily lives and well-being of patients in Japan compared to people without the condition.

Quick facts

Study typeObservational
Enrollment470 (estimated)
Ages18 Years and up
SexAll
SponsorBristol-Myers Squibb Industry-sponsored
Locations1 site (Minato-ku, Tokyo)
Trial IDNCT06181617 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate health-related quality of life in patients diagnosed with hypertrophic cardiomyopathy (HCM) in Japan. It consists of two phases: the first phase involves qualitative interviews with HCM patients to gather in-depth insights, while the second phase employs quantitative questionnaires to compare the quality of life between HCM patients and a control group from the general population. The study seeks to understand the impact of HCM on daily living and overall well-being.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older diagnosed with either obstructive or non-obstructive hypertrophic cardiomyopathy in Japan.

Not a fit: Patients with other forms of cardiomyopathy or those currently participating in other clinical trials may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the quality of life challenges faced by HCM patients, informing better management and treatment strategies.

How similar studies have performed: While there have been studies assessing quality of life in various cardiac conditions, this specific approach focusing on HCM in Japan is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria - hypertrophic cardiomyopathy group

* Participants diagnosed with non-obstructive or obstructive HCM in Japan
* Participants aged ≥18 years of age
* Participants who have been attending outpatient visits for HCM and who are referred to the study by the physician treating HCM
* Participants with HCM who are diagnosed as New York Heart Association (NYHA) functional classification 2-3 at enrolment
* Participants experiencing burden in their daily lives because of HCM (self-reported)

Inclusion Criteria - control group

* Participants aged ≥18 years of age
* Individuals from the general population who are enrolled in 3H Clinical Trial's consumer panel

Exclusion Criteria - hypertrophic cardiomyopathy group

* Participants who have ever been diagnosed with dilated cardiomyopathy or secondary cardiomyopathy, including cardiac amyloidosis, Fabry disease, or mitochondrial myopathy
* Participants who have previously participated or are currently participating in another clinical trial (not including observational studies)

Exclusion Criteria - control group

* Participants who have ever been diagnosed with non-obstructive or obstructive HCM
* Participants who have ever been diagnosed with either dilated cardiomyopathy or secondary cardiomyopathy, including cardiac amyloidosis, Fabry disease, or mitochondrial myopathy
* Participants who have previously participated or are currently participating in another clinical trial (not including observational studies)

Where this trial is running

Minato-ku, Tokyo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypertrophic Cardiomyopathy
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.