Assessing Peripheral Arterial Disease in Patients with Deep Vein Thrombosis
Official title: The Frequency of Peripheral Arterial Disease in Patients with Deep Vein Thrombosis of the Lower Limbs
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06806540 · Data updated 2026-11-12
This study looks at how common Peripheral Arterial Disease is in people with unprovoked Deep Vein Thrombosis and compares it to those with other types of DVT to see how their heart health is related.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 440 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Status | Recruiting |
| Started | June 10, 2021 |
| Main results expected | June 5, 2024 |
| Study ends | December 31, 2027 |
| Registry record updated | February 4, 2025 |
| Trial ID | NCT06806540 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 years with a diagnosis of unprovoked, provoked, or cancer-related DVT in the lower limbs.
✕Probably not a fit
Patients with upper limb DVT, superficial venous thrombosis, or DVT associated with central venous catheters may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the frequency of Peripheral Arterial Disease (PAD) and cardiovascular risk factors in patients diagnosed with unprovoked Deep Vein Thrombosis (DVT) of the lower limbs. It compares these patients with those who have provoked DVT or cancer-related DVT. The study will also investigate the relationship between Ankle-Brachial Index (ABI) and Carotid Intima-Media Thickness (IMT) across different patient groups. Conducted at the Sant'Orsola Malpighi Polyclinic in Bologna, it includes both retrospective and prospective patient data.
Why it matters
Potential benefit: If successful, this study could enhance understanding of cardiovascular risks in DVT patients, potentially leading to improved management strategies.
How similar studies have gone: While studies on DVT and PAD exist, this specific observational approach focusing on unprovoked DVT is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Diagnosis of unprovoked, provoked, or cancer-related DVT * Diagnosis of DVT in the lower limbs, both proximal and distal, subjected to compression ultrasound within 6 months of diagnosis * Ability to provide informed consent Exclusion Criteria: * Diagnosis of upper limb DVT or DVT in other locations, if not concurrent with lower limb DVT * Diagnosis of superficial venous thrombosis (SVT), if not concurrent with lower limb DVT * Diagnosis of DVT associated with central venous catheters (CVC) * Presence of epithelial or basal cell carcinomas, as they are associated with a low risk of deep vein thrombosis
Where it's running
-
IRCCS Azianda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy Recruiting
Study contacts
- Principal investigator: Benilde Cosmi, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Benilde Cosmi, MD
- Email: benilde.cosmi@unibo.it
- Phone: 051 2142483
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.