Assessing pain in ICU patients with delirium using pupillometry

Use of Automated Pupillometry for Pain Assessment in ICU Patients with Delirium

St. Anne's University Hospital Brno, Czech Republic · NCT05811208

This study is testing a new way to measure pain in ICU patients with delirium using eye measurements to see if it helps improve their pain management.

Quick facts

Study typeObservational
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorSt. Anne's University Hospital Brno, Czech Republic (other)
Locations1 site (Brno, Czech republic)
Trial IDNCT05811208 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate pain assessment methods in intensive care unit (ICU) patients who are experiencing delirium. It will utilize automated pupillometry alongside established pain assessment scales, such as the Visual Analogue Scale (VAS), Behavioral Pain Scale (BPS), and Critical Care Observational Tool (CPOT). The study will periodically assess the incidence of delirium and pain in patients after surgery, while also recording medication and vital signs. The goal is to improve pain management in patients who may struggle to communicate their pain due to delirium.

Who should consider this trial

Good fit: Ideal candidates include postoperative patients in the ICU who can undergo the CAM-ICU test.

Not a fit: Patients with eye diseases, brain injuries, strokes, epilepsy, or neuromuscular diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance pain assessment and management in ICU patients, leading to better patient outcomes.

How similar studies have performed: Previous studies have shown positive results using pupillometry for nociception assessment, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patient after surgery
* possibility to perform CAM - ICU test (patients with Richmond Agitation-Sedation Scale -2 to +2)

Exclusion Criteria:

* eye diseases
* brain injury
* stroke
* epilepsy
* neuromuscular diseases

Where this trial is running

Brno, Czech republic

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Delirium, Pain, Postoperative, pupillometry, delirium, pain

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.