Assessing oxygen pressure and arterial waveforms during exercise for peripheral artery disease
Analysis of Arterial Waveforms and Oxygen Pressure During Supervised Exercise for Peripheral Artery Disease
NA · University Hospital, Caen · NCT05818046
This study is testing how exercise therapy affects oxygen levels and blood flow in people with peripheral artery disease to see if it helps them improve over time.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 36 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Caen (other) |
| Locations | 1 site (Caen, Normandie) |
| Trial ID | NCT05818046 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate changes in oxygen pressure and arterial waveforms in patients with peripheral arterial disease (PAD) undergoing supervised exercise therapy. It will measure the effectiveness of this therapy by assessing whether significant increases in oxygen pressure can be observed at 3, 6, or 9 weeks. The study will utilize transcutaneous oximetry and arterial Doppler waveform analysis to gather data on patient responses to exercise. This research is particularly important as it seeks to fill gaps in understanding the predictive value of these measurements during exercise therapy.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with PAD who experience intermittent claudication and are prescribed supervised exercise therapy.
Not a fit: Patients with rest ischemia, chronic respiratory failure, or those living more than 100 km from the study site may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the effectiveness of supervised exercise therapy for patients with peripheral artery disease.
How similar studies have performed: While supervised exercise therapy is a standard treatment for PAD, this specific approach of assessing oxygen pressure and arterial waveforms during therapy has not been previously studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * PAD with intermittent claudication * SET prescribed * ABI \< 0.9 * Beneficiary of French health care insurance Exclusion Criteria: * PAD with rest ischemia * Chronic respiratory failure * Acute decompensated disease * Lower limb prosthesis * Pregnant women and breastfeeding mothers * Place of residence more than 100 km from Caen University Hospital
Where this trial is running
Caen, Normandie
- CHU Caen Normandie — Caen, Normandie, France (RECRUITING)
Study contacts
- Study coordinator: Lanéelle
- Email: drci-secretariat@chu-caen.fr
- Phone: 02 31 06 57 81
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Peripheral Arterial Disease, Supervised exercise therapy, arterial waveform, transcutaneous oxygen pressure