Assessing muscle loss in lung cancer patients using imaging techniques

Study on the Value of Musculoskeletal Cross-modal Imaging Assessment System in the Diagnosis and Prognosis of Sarcopenia in Lung Cancer Patients

This study is testing a new way to use ultrasound and scans to find muscle loss in lung cancer patients to see if catching it early can help improve their treatment and recovery.

Quick facts

• Study type: Observational
• Enrollment: 1500 (estimated)
• Ages: 40 Years to 100 Years
• Sex: All
• Sponsor: West China Hospital (other)
• Locations: 1 site (Chengdu, Sichuan)
• Trial ID: NCT06327594 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a combined imaging assessment system using ultrasound and abdominal CT/MRI to diagnose and monitor sarcopenia in lung cancer patients. It focuses on understanding the relationship between sarcopenia and lung cancer prognosis, particularly during the perioperative period. By identifying sarcopenia early, the study seeks to improve patient outcomes through timely nutritional support and interventions. The research will also explore the long-term prognosis of lung cancer patients with sarcopenia.

Who should consider this trial

Good fit: Ideal candidates include hospitalized patients scheduled for radical resection of lung cancer who have undergone a CT/MRI examination within the past week.

Not a fit: Patients with amputated limbs, severe edema, implantable pacemakers, or those unable to complete the study due to impaired consciousness or poor health may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic methods and better management strategies for lung cancer patients suffering from sarcopenia.

How similar studies have performed: While the approach of using combined imaging techniques is innovative, previous studies have indicated a significant prevalence of sarcopenia in lung cancer patients, suggesting a need for improved diagnostic methods.

Eligibility criteria

Inclusion Criteria:

1. Hospitalized patients scheduled for radical resection of lung cancer.
2. With a CT/MRI examination within 1 week.
3. The compliance of examination was good.

Exclusion Criteria:

1. Amputated arm or leg.
2. Severe oedema (oedema higher than knee level).
3. Implantable pacemaker.
4. Impaired consciousness, poor general health, or other reasons that would prevent the individual from completing the study.

Where this trial is running

Chengdu, Sichuan

• Xinyi Tang — Chengdu, Sichuan, China (RECRUITING)

Study contacts

• Principal investigator: Xinyi Tang — Department of Medical Ultrasound, West China Hospital, Sichuan University
• Study coordinator: Xinyi Tang, Dr.

Conditions: Sarcopenia, Lung Cancer, Ultrasound