Assessing lung and heart effects of vaping in adults

VapALERT: A Prospective, Exploratory and Adaptive Cohort Study to Identify Symptomatic and Asymptomatic Pulmonary and Cardiovascular Effects of Vaping

Laval University · NCT06291597

This study is testing how vaping affects the lungs and heart in adults who use e-cigarettes over five years.

Quick facts

Study typeObservational
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorLaval University (other)
Locations1 site (Québec)
Trial IDNCT06291597 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the pulmonary and cardiovascular effects of vaping among adult electronic cigarette users over a five-year period. Participants will undergo biannual visits where they will perform various pulmonary function tests and complete questionnaires regarding their vaping and smoking habits. Additionally, blood samples and sputum inductions will be conducted to analyze inflammation markers and cell counts. The study aims to provide insights into the health impacts of daily vaping.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 years or older who are daily electronic cigarette users.

Not a fit: Patients who are pregnant or breastfeeding will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the health risks associated with vaping, potentially leading to better prevention and treatment strategies.

How similar studies have performed: While there have been studies on vaping, this specific long-term observational approach focusing on both pulmonary and cardiovascular effects is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older
* Daily electronic cigarette user
* No respiratory infection in the 4 weeks before a visit

Exclusion Criteria:

* Women who are pregnant or breast-feeding.

Where this trial is running

Québec

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Vaping, Electronic Cigarette Use, Vape, Electronic cigarette, Electronic and vaping acute lung injury, EVALI

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.