Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Assessing liver fat changes in cancer patients undergoing chemotherapy

Official title: Feasibility Study of Deep Learning-based MDixon Quant for Quantitative Assessment of Chemotherapy-induced Fatty Liver

Run by Yunnan Cancer Hospital · NCT06735118 · Data updated 2026-11-12

This study is testing a new scanning method to see how chemotherapy affects liver fat in cancer patients before and after treatment.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment120 (estimated)
SponsorYunnan Cancer Hospital
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Kunming, Yunnan)
StatusRecruiting
StartedDecember 25, 2023
Main results expectedDecember 30, 2024
Study endsDecember 30, 2024
Registry record updatedDecember 16, 2024
Trial IDNCT06735118 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are cancer patients who have not been diagnosed with fatty liver and are undergoing neoadjuvant or adjuvant chemotherapy.

Probably not a fit

Patients with existing liver lesions or those who cannot undergo MRI due to contraindications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to quantitatively evaluate changes in liver fat content in cancer patients before and after receiving neoadjuvant chemotherapy. It utilizes a novel deep learning-based mDixon Quant scanning technique that automates the segmentation and measurement of liver fat, improving accuracy and efficiency compared to traditional methods. By employing a threshold extraction method, the study seeks to provide a comprehensive assessment of liver fat fraction, which is crucial for understanding the impact of chemotherapy on liver health.

Why it matters

Potential benefit: If successful, this study could lead to more accurate monitoring of liver health in cancer patients undergoing chemotherapy, potentially improving treatment outcomes.

How similar studies have gone: While this approach is innovative, similar studies utilizing advanced imaging techniques for liver assessment have shown promise, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. CT/B ultrasound showed no fatty liver
2. No MRI contraindications, including pacemaker, stent, metal implant, or claustrophobia
3. Received neoadjuvant/adjuvant chemotherapy

Exclusion Criteria:

1. Missing follow-up information
2. Liver lesions (metastases, hemangioma, etc.)
3. Poor image quality

Where it's running

  • Yunnan Cancer Hospital
    Kunming, Yunnan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.