Assessing liver fat changes in cancer patients undergoing chemotherapy
Official title: Feasibility Study of Deep Learning-based MDixon Quant for Quantitative Assessment of Chemotherapy-induced Fatty Liver
Run by Yunnan Cancer Hospital · NCT06735118 · Data updated 2026-11-12
This study is testing a new scanning method to see how chemotherapy affects liver fat in cancer patients before and after treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | Yunnan Cancer Hospital Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Kunming, Yunnan) |
| Status | Recruiting |
| Started | December 25, 2023 |
| Main results expected | December 30, 2024 |
| Study ends | December 30, 2024 |
| Registry record updated | December 16, 2024 |
| Trial ID | NCT06735118 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are cancer patients who have not been diagnosed with fatty liver and are undergoing neoadjuvant or adjuvant chemotherapy.
✕Probably not a fit
Patients with existing liver lesions or those who cannot undergo MRI due to contraindications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to quantitatively evaluate changes in liver fat content in cancer patients before and after receiving neoadjuvant chemotherapy. It utilizes a novel deep learning-based mDixon Quant scanning technique that automates the segmentation and measurement of liver fat, improving accuracy and efficiency compared to traditional methods. By employing a threshold extraction method, the study seeks to provide a comprehensive assessment of liver fat fraction, which is crucial for understanding the impact of chemotherapy on liver health.
Why it matters
Potential benefit: If successful, this study could lead to more accurate monitoring of liver health in cancer patients undergoing chemotherapy, potentially improving treatment outcomes.
How similar studies have gone: While this approach is innovative, similar studies utilizing advanced imaging techniques for liver assessment have shown promise, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. CT/B ultrasound showed no fatty liver 2. No MRI contraindications, including pacemaker, stent, metal implant, or claustrophobia 3. Received neoadjuvant/adjuvant chemotherapy Exclusion Criteria: 1. Missing follow-up information 2. Liver lesions (metastases, hemangioma, etc.) 3. Poor image quality
Where it's running
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Yunnan Cancer Hospital
Kunming, Yunnan, China Recruiting
Study contacts
- Study coordinator: Lizhu Liu, Graduate
- Email: liulizhu2022@163.com
- Phone: 18287509587
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.