Assessing immune response in children with Lyme disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the immune response against Borrelia burgdorferi in children diagnosed with Lyme disease. It will develop a new diagnostic tool using the Bb-specific ASC ELISpot assay to improve early diagnosis, addressing the limitations of current testing methods. The study will enroll 502 patients aged 0-17 years who present with symptoms suggestive of Lyme disease, alongside healthy controls. Blood samples will be collected at initial hospital visits and follow-up appointments to analyze immune cell responses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients presenting at the ED with differential diagnosis of LD according to the treating physician

Exclusion Criteria:

* Patients will be excluded in cases of primary or secondary immunodeficiency

Where it's running

• Chidren's Hospital Zurich
  Zurich, Switzerland Recruiting

Study contacts

• Principal investigator: Patrick M Meyer Sauteur, MD PhD — Division of infectious diseases Univesity Children's Hospital Zurich
• Study coordinator: Patrick M Meyer Sauteur, MD PhD
• Email: patrick.meyersauteur@kispi.uzh.ch
• Phone: 0041 44 266 78 96

Similar studies

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.