Assessing Helicobacter Pylori Infection Rates in Families in Jiangsu
The Prevalence of Family-unit Helicobacter Pylori Infection in Jiangsu Based on Non-invasive PCR in Stool
This study looks at how common Helicobacter pylori infections are in families in Jiangsu, China, and checks if the bacteria are resistant to antibiotics.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4000 (estimated) |
| Ages | 6 Years and up |
| Sex | All |
| Sponsor | Nanjing First Hospital, Nanjing Medical University Academic / other |
| Locations | 16 sites (Changzhou, Jiangsu and 15 other locations) |
| Trial ID | NCT05654857 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the prevalence of Helicobacter pylori infection and the rates of antimicrobial resistance within family units in Jiangsu, China. The research involves collecting stool samples from community members, which will be analyzed using real-time PCR to detect the presence of the infection and any drug-resistant gene mutations. The study focuses on understanding the infection dynamics within families to inform public health strategies. Participation requires informed consent and adherence to specific eligibility criteria.
Who should consider this trial
Good fit: Ideal candidates for this study are community members from Jiangsu who can provide stool samples and meet the study's inclusion criteria.
Not a fit: Patients who have recently used antibiotics or other medications affecting Helicobacter pylori, or those unable to provide adequate stool samples, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the prevalence of Helicobacter pylori infections and resistance patterns, potentially guiding more effective treatment strategies.
How similar studies have performed: While similar studies have been conducted, this specific focus on family units and antimicrobial resistance in Jiangsu presents a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. community population 2. Fecal samples can be obtained, and the sample volume meets the requirements of the collection tube instructions 3. Only one person per family can be selected 4. Voluntarily participated in this study and signed an informed consent form Exclusion Criteria: 1. The collector does not cooperate or has poor compliance; 2. Adequate and qualified fecal samples could not be obtained; 3. Stool samples were collected during diarrhea or constipation; 4. Antibiotics, bismuth preparations, proton pump inhibitors and other Hp sensitive drugs have been used within one month.
Where this trial is running
Changzhou, Jiangsu and 15 other locations
- Changzhou Traditional Chinese medical hospital,Affiliated to Nanjing University of Chinese Medicine — Changzhou, Jiangsu, China (Not_yet_recruiting)
- JinHu county people's hospital — Huaian, Jiangsu, China (Recruiting)
- The 1st people's hospital of Lianyungang — Lianyungang, Jiangsu, China (Recruiting)
- Nanjing First Hospital, Nanjing Medical University — Nanjing, Jiangsu, China (Recruiting)
- Affiliated Hospital of Nantong University — Nantong, Jiangsu, China (Recruiting)
- Rudong County People's Hospital — Nantong, Jiangsu, China (Recruiting)
- The Affiliated Shuyang Hospital of Xuzhou Medical University — Suqian, Jiangsu, China (Recruiting)
- Changshu No.1 People's Hospital — Suzhou, Jiangsu, China (Recruiting)
- Department of Gastroenterology Wuxi People's Hospital Affiliated to Nanjing Medical University — Wuxi, Jiangsu, China (Recruiting)
- The First People's Hospital of Xuzhou, Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University — Xuzhou, Jiangsu, China (Recruiting)
- Dongtai People's Hospital — Yancheng, Jiangsu, China (Not_yet_recruiting)
- Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School — Yancheng, Jiangsu, China (Not_yet_recruiting)
- Affiliated Hospital of Yangzhou University — Yangzhou, Jiangsu, China (Recruiting)
- Affiliated Hospital of Jiangsu University — Zhenjiang, Jiangsu, China (Not_yet_recruiting)
- Changshu Hospital Affiliated to Nanjing University of Chinese Medicine — Suzhou, China (Not_yet_recruiting)
- People's hospital of Yangzhong City — Zhenjiang, China (Not_yet_recruiting)
Study contacts
- Study coordinator: Zhenyu Zhang
- Email: zzy6565@sina.com
- Phone: +86 025-87726248
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.