Clinical trial Recruiting at 1 site Observational Ages 18 to 75

Assessing heart tissue damage in patients with heart aneurysms after a heart attack

Official title: Assessment of Myocardial Fibrosis by 18F-FAPI/PET-CT in Patients With Myocardial Infarction-associated Ventricular Aneurysm

Run by RenJi Hospital · NCT06994221 · Data updated 2026-11-12

This study is testing how heart tissue damage looks in patients with heart aneurysms after a heart attack using special imaging to see if it helps understand their condition better.

More Acute Myocardial Infarction trials

Quick facts

Study typeObservational
Ages18 Years to 75 Years
SexAll
Enrollment20 (estimated)
SponsorRenJi Hospital
Academic / other
Locations1 site (Shanghai)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedJuly 31, 2025
Study endsDecember 31, 2025
Registry record updatedMay 29, 2025
Trial IDNCT06994221 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-75 diagnosed with STEMI or NSTEMI and have a ventricular aneurysm.

Probably not a fit

Patients under 18, pregnant or breastfeeding women, and those with allergies to radio tracers may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate myocardial fibrosis in patients with ventricular aneurysm following an acute myocardial infarction using 18F-FAPI PET/CT imaging. Participants will undergo a PET/CT scan during their hospital stay, along with serial echocardiography and follow-up assessments over one year. The study will analyze the relationship between the imaging results and clinical markers of disease progression, providing insights into the nature of myocardial fibrosis in these patients.

Why it matters

Potential benefit: If successful, this study could enhance understanding of myocardial fibrosis and improve prognosis for patients with heart aneurysms after a heart attack.

How similar studies have gone: While the use of PET imaging in cardiac conditions is established, this specific approach using 18F-FAPI for myocardial fibrosis assessment is novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 18-75 years old
* Diagnosed with STEMI or NSTEMI (ACC/AHA guidelines)
* Half male and half female
* Undergo CAG and PCI treatment;
* Receive either echocardiography or CMR to identify a ventricular aneurysm;
* Written informed consent

Exclusion Criteria:

* Patients under the age of 18 years old;
* Patients who are pregnant/breastfeeding;
* Patients who has a previous history of allergy to radio tracers.

Where it's running

  • Renji Hospital
    Shanghai, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.