Assessing heart function changes after diuretic treatment in heart failure patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study involves 50 patients admitted to the cardiac care unit who require diuretic therapy for acute decompensated heart failure. It aims to evaluate the effectiveness of non-invasive cardiac output monitoring using the Starling Fluid Management System to assess volume status in these patients. Participants will be monitored for changes in stroke volume index following diuresis, providing insights into fluid management in heart failure treatment. The study focuses on patients who are expected to need intravenous diuretics for more than 24 hours.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Diagnosis of congestive acute decompensated heart failure (preserved or reduced ejection fraction) requiring clinically indicated IV diuresis
2. Admission to coronary/cardiac intensive care unit or cardiac step down unit
3. Able to provide written informed consent
4. Anticipated need for IV diuretics \> 24 hrs

Exclusion Criteria:

1. Prisoner, pregnancy or post-partum stage, or age \< 18 years
2. Known allergy to sensory material or gel
3. End stage renal disease or need for CRRT
4. Inability or contraindication to do a passive leg raise with both extremities (i.e., balloon pump, impella, spinal injury, amputation)
5. Other situation that might increase subject risk, interfere with study procedures, or confound study findings based on the opinion of the clinician/investigator
6. Inability to provide informed consent

Where it's running

• NYU Langone Health
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Carlos Alviar, MD — NYU Langone Health
• Study coordinator: Carlos Alviar, MD
• Email: carlos.alviar@nyulangone.org
• Phone: 212-263-6635

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.