Assessing health outcomes in critically ill patients
Critical Health Assessment and Outcomes Score/Study
This study is trying to find early warning signs of serious illness in critically ill patients to help doctors treat them sooner and improve their chances of recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Johns Hopkins University Academic / other |
| Locations | 3 sites (Indianapolis, Indiana and 2 other locations) |
| Trial ID | NCT02766166 on ClinicalTrials.gov |
What this trial studies
The CHAOS initiative aims to identify early signs of critical illness in patients through an observational approach that integrates various scientific disciplines. By analyzing physiological signals, the study seeks to enhance conventional clinical predictors and provide unique prognostic insights. The primary objective is to reduce mortality and complications by detecting subclinical critical illness before it manifests into severe conditions. This proactive identification could allow healthcare providers to intervene earlier and more effectively.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 to 100 years who are admitted to a hospital bed or operating room with telemetry monitoring.
Not a fit: Patients under 18 years of age will not benefit from this study as they are excluded from participation.
Why it matters
Potential benefit: If successful, this approach could significantly reduce mortality and morbidity in critically ill patients by enabling earlier interventions.
How similar studies have performed: While this study employs a novel approach, previous observational studies have shown promise in early identification of critical illness, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients age 18-100 years admitted to a bed or OR with telemetry monitoring capability will be included. Exclusion Criteria: * Children (individuals \<18 years of age).
Where this trial is running
Indianapolis, Indiana and 2 other locations
- Indiana University — Indianapolis, Indiana, United States (Not_yet_recruiting)
- Johns Hopkins University — Baltimore, Maryland, United States (Not_yet_recruiting)
- University of Cincinnati — Cincinnati, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Deeptankar DeMazumder, MD, PhD
- Email: DDeMazu@iu.edu
- Phone: 513-558-1035
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.