Assessing exercise capacity and prognosis in patients with cardiac amyloidosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on understanding cardiac amyloidosis by evaluating the exercise capacity and prognostic implications for affected patients. Over a two-year period, participants will be assessed every six months to monitor changes in their exercise performance and other clinical parameters. The study aims to develop a prognostic tool similar to the MECKI score to evaluate the risk of adverse events based on exercise capacity. Additionally, it will compare findings with existing data from heart failure patients to identify differences in prognosis.

Why it matters

Who can join: the full rules

Inclusion criteria

* Age \> 18 years
* Diagnosis of cardiac amyloidosis obtained by MRI or scintigraphy
* Ability to perform a cardiopulmonary exercise test

Exclusion criteria

* severe obstructive pulmonary disease
* exercise-induced angina
* significant ECG changes
* presence of clinical comorbidities that interfere with exercise performance

Where it's running

• Centro Cardiologico Monzino, Irccs
  Milan, Italy, Italy Recruiting

Study contacts

• Study coordinator: piergiuseppe Agostoni, MD, PhD
• Email: piergiuseppe.agostoni@cardiologicomonzino.it
• Phone: 0258002772

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using [64Cu]FBP8 PET/MR to find intracardiac blood clots in cardiac amyloidosis

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• Chest pain screening for hidden cardiac amyloidosis

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• Using advanced heart MRI to improve diagnosis and risk prediction for rare cardiomyopathies

  This project tests whether advanced cardiac MRI techniques can help diagnose and predict future risk for people with rare heart muscle diseases like Danon, Fabry, cardiac amyloidosis, Noonan syndrome, and cardiac sarcoidosis.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT07336394

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.