Assessing delirium in older adults with mild cognitive impairment
A Prospective, Longitudinal Cohort Study of the Incidence of Dementia After the Onset of Delirium in Patients With Mild Cognitive Impairment: MDD Cohort (Mild Cognitive Impairment Delirium Dementia)
This study looks at how delirium affects older adults with mild cognitive impairment to see what risks it brings and how it might lead to dementia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 163 (estimated) |
| Ages | 65 Years and up |
| Sex | All |
| Sponsor | Keimyung University Dongsan Medical Center Academic / other |
| Locations | 2 sites (Daegu, Gyeongsangnam-do, and 1 other locations) |
| Trial ID | NCT05113446 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify the degree of delirium in older adults diagnosed with mild cognitive impairment and to explore the associated risk factors. It will analyze clinical consequences such as mortality, hospital stay, and medical expenses related to delirium incidence. Additionally, the study will track the conversion rate to dementia in subjects with mild cognitive impairment and delirium, while developing an AI algorithm to predict dementia transition based on the findings over three years.
Who should consider this trial
Good fit: Ideal candidates are patients aged 65 and older with a diagnosis of mild cognitive impairment.
Not a fit: Patients with severe psychiatric or neurological conditions, or those unable to participate in delirium assessments due to sensory impairments, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prediction and management of dementia in patients with mild cognitive impairment.
How similar studies have performed: While similar studies have explored delirium and cognitive impairment, this study's specific approach and AI development for predicting dementia transition is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients 65 years of age or older who are admitted to a LTC * Patients diagnosed with mild cognitive impairment by doctors * Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination Exclusion Criteria: * Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems * Patients with serious psychiatric or neurological diagnosis,Patients who expire or were transferred on the day of admission - * Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances
Where this trial is running
Daegu, Gyeongsangnam-do, and 1 other locations
- Yangsan Seoul long-term care (LTC) facilities — Daegu, Gyeongsangnam-do,, Korea, Republic of (Recruiting)
- Gunsan Chamsarang long-term care (LTC) facilities — Daegu, Jeollabuk-do, Korea, Republic of (Not_yet_recruiting)
Study contacts
- Study coordinator: Kyoung ja Moon, doctor
- Email: kjmoon2150@gmail.com
- Phone: +821023026302
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.