Assessing changes in attention after a focal seizure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate how attentional control is affected following a focal seizure in patients with epilepsy. The researchers will conduct a prospective longitudinal assessment of brain activity and cognitive performance during the peri-ictal period using high-resolution EEG and event-related potentials. By focusing on patients undergoing pre-surgery work-up for focal epilepsy, the study seeks to understand the disorganization of neural networks involved in attentional control post-seizure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age superior to 18 and under 80
* Focal epilepsy with indication to pre-surgery work-up and 5 days programmed hospitalization dedicated to this work-up
* Normal global cognitive performance (standard progressive Raven matrices score \> 5th percentile)
* Be affiliated to the social security system
* Have signed an informed consent

Exclusion Criteria:

* Pregnancy or breastfeeding
* Not able to give consent (Article 1121-8 of the CSP)
* Vulnerable person
* Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP)
* Guardianship
* Have a high probability of not respecting the protocol or of abandoning the study
* Absence of any epileptic seizure recorded during the hospitalization
* Recurrent seizures preventing the recording of at least 24 hours without any seizure following a seizure.

Where it's running

• University Hospital,
  Lille, France Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Preoperative speech rehabilitation for patients with drug-resistant temporal epilepsy

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  Recruiting at 6 sites Assistance Publique Hopitaux De Marseille · Bordeaux and 11 other locations · NCT05609084

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.