Assessing breathing effort in COVID-19 patients with respiratory failure
Inspiratory Effort Assessment in Patients With COVID-19 Pneumonia Undergoing Non Invasive Respiratory Support
This study is testing how breathing effort in COVID-19 patients with severe respiratory failure changes when they receive non-invasive support to help improve their care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of Modena and Reggio Emilia Academic / other |
| Locations | 1 site (Modena) |
| Trial ID | NCT04666246 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates esophageal pressure in patients experiencing acute respiratory failure due to COVID-19 while receiving non-invasive respiratory support. By measuring this pressure, the study aims to gain insights into the respiratory mechanics of affected patients. The findings could help improve the management of respiratory support in COVID-19 cases. The study is conducted at the University Hospital of Modena.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with COVID-19 who are experiencing acute respiratory failure and are receiving non-invasive respiratory support.
Not a fit: Patients who require immediate endotracheal intubation or have chronic respiratory diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding of respiratory mechanics in COVID-19 patients, leading to better treatment strategies.
How similar studies have performed: While the specific approach of measuring esophageal pressure in this context may be novel, similar studies assessing respiratory mechanics in acute respiratory failure have shown promise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * COVID-19 * Acute respiratory failure undergoing non-invasive respiratory support Exclusion Criteria: * Need for immediate endotracheal intubation * Chronic respiratory diseases
Where this trial is running
Modena
- University Hospital of Modena — Modena, Italy (Recruiting)
Study contacts
- Study coordinator: Roberto Tonelli, MD
- Email: roberto.tonelli@me.com
- Phone: 0039 0594225934
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.