Assessing brain function in patients with brain tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect and analyze various imaging data, including functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), and magnetoencephalography (MEG), from patients with primary or metastatic brain tumors located near eloquent brain areas. The research will evaluate how well these imaging modalities predict the location of critical brain functions before surgery and assess changes in brain function and plasticity after tumor removal. Participants will undergo a series of pre-operative evaluations, intra-operative mapping, and post-operative assessments to monitor their neurological status and recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 19 years and older
* Brain tumor in or near eloquent brain regions that is appropriate for attempted resection
* Appropriate body habitus and mental status/capacity to participate with non-invasive or invasive mapping
* Benign or malignant intra-axial brain tumor
* Primary or metastatic intra-axial brain tumor

Exclusion Criteria:

* Any contraindication to MRI (i.e. implanted devices)
* Inappropriate body habitus or mental status/capacity to participate with non-invasive or invasive mapping in a safe and reliable manner
* Declining to participate
* Lacks capacity to understand the study or consent for themselves
* Neurologic status which precludes testing (poor function- not testable)
* Positive pregnancy test
* End stage renal disease or severe renal dysfunction

Where it's running

• University of Nebraska Medical Center
  Omaha, Nebraska, United States Recruiting

Study contacts

• Principal investigator: Michele Aizenberg, MD — University of Nebraska
• Study coordinator: Dulce Maroni, PhD
• Email: dmaroni@unmc.edu
• Phone: 402-836-9751

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.