Assessing Barrett's Esophagus in Patients with Anorexia Nervosa and Purging Behaviors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the presence of Barrett's esophagus (BE) in individuals diagnosed with anorexia nervosa who exhibit purging behaviors, such as vomiting and rumination. It will utilize non-endoscopic testing methods to identify BE in a cohort that typically does not meet the standard screening guidelines. The study focuses on patients aged 18-65 with a history of purging for at least five years, who are admitted to a specialized center for eating disorders. By examining this population, the study seeks to provide insights into the prevalence of BE in younger patients with severe eating disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with an eating disorder diagnosis that includes purging history
* Ages 18-65
* Purging history =\>5 years
* Purging or rumination at a minimum of once daily upon admission.
* Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition

Exclusion Criteria:

* Any eating disorder diagnosis that does not include purging behaviors
* Ages under 18 and over 65
* Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background)
* Received mandated care at time of enrollment
* Inability to consent to participate in the research

Where it's running

• ACUTE Center for Eating Disorders and Severe Malnutrition
  Denver, Colorado, United States Recruiting
• Denver Health and Hospital Authority
  Denver, Colorado, United States Recruiting
• Denver Health and Hospital Authority
  Denver, Colorado, United States Recruiting

Study contacts

• Principal investigator: Allison Nitsch, MD — Denver Health and Hospital Authority
• Study coordinator: Marina J Foster, BA
• Email: marina.foster@dhha.org
• Phone: 303-602-1913

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Itraconazole with endoscopic ablation to prevent esophageal cancer in high‑risk Barrett's esophagus

  This study tests if adding itraconazole to the standard endoscopic ablation can better prevent esophageal cancer in people with high-risk Barrett's esophagus.

  Recruiting at 4 sites Phase 2 National Cancer Institute (NCI) · Kansas City, Kansas and 5 other locations · NCT06732388

• Detecting Barrett's Esophagus in Patients Without GERD Symptoms

  This study is testing a new way to find Barrett's esophagus in people who don’t have GERD symptoms by using a simple capsule test instead of the usual endoscopy.

  Recruiting at 5 sites Case Comprehensive Cancer Center · Aurora, Colorado and 4 other locations · NCT06687603

• Using a swallowable sponge to collect esophageal samples for Barrett's esophagus detection

  This study is testing a swallowable sponge to see if it can safely collect samples from the esophagus to help detect Barrett's esophagus and esophageal cancer in patients who may have these conditions.

  Recruiting at 3 sites Mayo Clinic · Scottsdale, Arizona and 4 other locations · NCT06071845

• Registry for patients undergoing esophageal cancer screening

  This study is collecting information from patients getting screened for Barrett Esophagus and Esophageal Adenocarcinoma using a new test to see how well it works and how patients feel about the process.

  Recruiting PAVmed Inc. · Lake Forest, California · NCT05965999

• Comparing surveillance and therapy for Barrett's esophagus with low-grade dysplasia

  This study is testing whether regular check-ups or a treatment to remove precancerous cells is better for people with Barrett's esophagus and low-grade dysplasia.

  Recruiting at 28 sites University of Colorado, Denver · Birmingham, Alabama and 29 other locations · NCT05753748

• Comparing biopsy methods for monitoring Barrett's Esophagus

  This study is testing whether a new biopsy method called WATS is better than the usual random biopsies for monitoring patients with Barrett's Esophagus who are at high risk for serious complications.

  Recruiting Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam, North Holland · NCT05642338

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.