Assessing and classifying children with Juvenile Idiopathic Arthritis
Clinical, Laboratory and Ultrasound Stratification of Patients With Juvenile Idiopathic Arthritis and Outcomes Evaluation During Transition to Adult Care
This study is trying to improve how we classify Juvenile Idiopathic Arthritis in children to help doctors provide better and more personalized treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | IRCCS Burlo Garofolo Academic / other |
| Locations | 2 sites (Trieste and 1 other locations) |
| Trial ID | NCT06007456 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on Juvenile Idiopathic Arthritis (JIA), the most common chronic rheumatologic condition in children. It aims to improve the classification of JIA by examining clinical, laboratory, and ultrasound data to better differentiate between the various forms of the disease. The study seeks to address the limitations of the current International League of Associations for Rheumatology (ILAR) classification, which may group distinct diseases together and overlook important similarities with adult arthritis. By refining the classification system, the study hopes to enhance personalized treatment approaches for affected children.
Who should consider this trial
Good fit: Ideal candidates for this study are children under 18 years old with arthritis persisting for at least 6 weeks and no known cause.
Not a fit: Patients with systemic onset Juvenile Idiopathic Arthritis or those with arthritis due to pre-existing inflammatory disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and tailored treatment plans for children with Juvenile Idiopathic Arthritis.
How similar studies have performed: While the approach to refining JIA classification is important, it is not widely tested, making this study a novel endeavor.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects under the age of 18 years * Arthritis persisting for at least 6 weeks with no known cause Exclusion Criteria: * No consent from the patients' guardians * Patients with Systemic onset Juvenile Idiopathic Arthritis * Patients who developed arthritis on a pre-existing inflammatory disorder such as Inflammatory Bowel Disease, and had received previous treatments
Where this trial is running
Trieste and 1 other locations
- IRCCS Burlo Garofolo — Trieste, Italy (Recruiting)
- (Department of Medical and Biological Sciences, Rheumatology Clinic, University of Udine — Udine, Italy (Recruiting)
Study contacts
- Study coordinator: Serena Pastore, MD
- Email: serena.pastore@burlo.trieste.it
- Phone: +390403785477
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.