Assessing a decision aid for colorectal cancer screening

Pilot Randomized Controlled Trial Assessing the Impact of Protect Your Colon™ on Colorectal Cancer Screening Behaviors

Not applicable Interventional Cedars-Sinai Medical Center · NCT05929820

This study is testing a new tool called Protect Your Colon™ to see if it helps people make better decisions about colorectal cancer screening and actually get screened more often.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment184 (estimated)
Ages45 Years to 75 Years
SexAll
SponsorCedars-Sinai Medical Center Academic / other
Locations1 site (Los Angeles, California)
Trial IDNCT05929820 on ClinicalTrials.gov

What this trial studies

This research evaluates the effectiveness of Protect Your Colon™, a decision aid designed to enhance colorectal cancer (CRC) screening behaviors among patients. The study hypothesizes that by improving shared decision-making, the aid will help patients choose screening tests that align with their values and ultimately increase screening rates. A pilot randomized controlled trial will compare the outcomes of patients using Protect Your Colon™ against those receiving usual care, focusing on communication, intent to screen, and actual screening uptake.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 45 to 75 who are either not up-to-date with CRC screening or have never been screened.

Not a fit: Patients with a high risk for colorectal cancer or those who do not speak English may not benefit from this study.

Why it matters

Potential benefit: If successful, this could lead to increased colorectal cancer screening rates, improving early detection and outcomes for patients.

How similar studies have performed: Other studies have shown promising results with decision aids in improving screening rates, suggesting this approach has potential.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Individuals 45 to 75 years old
* No prior CRC screening or not up-to-date with CRC screening
* Not at high risk for CRC (e.g., inflammatory bowel disease, colon polyposis syndromes, family history of CRC)
* No prior colon polyps
* Additional inclusion criteria for participants recruited through Cint online survey panels: (i) appointment with a primary care provider up to 6 weeks from time of screening, and (ii) have Preferred Provider Organization (PPO) insurance.

Exclusion Criteria:

* Does not speak English
* Does not have internet access
* Any records flagged "break the glass" or "research opt out."

Where this trial is running

Los Angeles, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colorectal Cancer ScreeningDecision aidStool testColonoscopyCT scan
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.