ARTICE® real-world data collection for sepsis and septic shock

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 4 observational registry will record real-world clinical data on adult ICU patients treated with ARTICE® for sepsis, septic shock, or related immunoparalysis. Sites will collect baseline characteristics, treatment details, safety events, and clinical outcomes including SOFA score changes from day 0 to day 7. The project aims to identify patient subgroups with differing risk–benefit profiles and to document routine use patterns outside controlled trials. Initial enrollment is planned at participating hospitals offering ARTICE®, starting with Klinikum Magdeburg.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects ≥ 18 years who are planned to receive ARTICE® treatment during their ICU stay

Exclusion Criteria:

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Where it's running

• Klinikum Magdeburg, Klinik für Intensiv- und Rettungsmedizin
  Magdeburg, Germany Recruiting
• Johannes Wesling Klinikum, Universitätsklinik für Anästhesiologie, Intensiv & Notfallmedizin
  Minden, Germany Recruiting

Study contacts

• Principal investigator: Martin Sauer, Prof. Dr. med. — Klinikum Magdeburg, Klinik für Intensiv- & Rettungsmedizin
• Study coordinator: Jens Altrichter, Dr. med.
• Email: jens.altrichter@artcline.de
• Phone: +49 381 440 703 0

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.