Aromatherapy rehabilitation for chemotherapy-related taste and smell changes

Rehabilitation of Taste and Smell Disorders Associated With Chemotherapy Using Aromatherapy

Not applicable Interventional Médipôle Lyon-Villeurbanne · NCT07041710

We will try aromatherapy with essential oils to help cancer patients who have taste or smell changes from chemotherapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment104 (estimated)
Ages18 Years and up
SexAll
SponsorMédipôle Lyon-Villeurbanne Academic / other
Drugs / interventionschemotherapy
Locations1 site (Villeurbanne)
Trial IDNCT07041710 on ClinicalTrials.gov

What this trial studies

This interventional program uses olfactory rehabilitation with selected essential oils delivered in a day-hospital setting to retrain smell and potentially improve taste during chemotherapy. Participants will complete guided odor exposure sessions and fill out standardized taste and smell questionnaires to measure changes over time. The approach adapts olfactory training methods used for post-viral anosmia, applying them to chemotherapy-related sensory alterations. Eligible patients are those actively receiving chemotherapy who report taste or smell disturbances, while patients who have finished chemotherapy are excluded.

Who should consider this trial

Good fit: Adults currently receiving chemotherapy who report new or worsening taste or smell disturbances and can attend day-hospital sessions are ideal candidates.

Not a fit: Patients who have completed chemotherapy (who are explicitly excluded) or whose sensory changes are due to other irreversible causes may not benefit.

Why it matters

Potential benefit: If effective, the approach could restore or improve taste and smell and help patients eat better and feel more like themselves during chemotherapy.

How similar studies have performed: Olfactory training with essential oils has helped some people with post-viral smell loss, but applying it to chemotherapy-related taste and smell disorders is a relatively new and less-tested approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* cancer treated with chemotherapy
* patient with taste and/or smell disorders

Exclusion Criteria:

* patient at the end of chemotherapy treatment

Where this trial is running

Villeurbanne

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.