Anti-inflammatory diet plus non-surgical gum treatment
Official title: Evaluation of the Effects of Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy in Individuals With Periodontitis
Run by Recep Tayyip Erdogan University Training and Research Hospital · NCT07287540 · Data updated 2026-11-12
This research will test whether adding anti-inflammatory nutrition education to routine non-surgical periodontal therapy helps people with periodontitis who eat a pro-inflammatory diet.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 65 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Recep Tayyip Erdogan University Training and Research Hospital Academic / other |
| Locations | 1 site (Rize) |
| Status | Recruiting |
| Started | November 22, 2025 |
| Main results expected | July 3, 2026 |
| Study ends | July 4, 2026 |
| Registry record updated | June 23, 2026 |
| Trial ID | NCT07287540 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults diagnosed with periodontitis who are systemically healthy, non-smokers, not pregnant or lactating, have at least 20 teeth, a dietary inflammatory index > 0, and no recent antibiotics, corticosteroids, or anti-inflammatory drug use are ideal candidates.
✕Probably not a fit
People with systemic diseases, active smokers, pregnant or lactating individuals, those with fewer than 20 teeth, or those without a pro-inflammatory diet are unlikely to benefit from this specific intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
One hundred adults with a pro-inflammatory dietary index (upper two quartiles) will be enrolled and divided into four groups based on dietary quartile and whether they receive nutrition education. All participants will receive non-surgical periodontal treatment, while half will also receive anti-inflammatory nutrition education. Outcomes include clinical periodontal parameters and biomarker measurements from gingival crevicular fluid and serum collected at baseline and follow-up. Group comparisons will be used to see whether the nutrition education is associated with differences in clinical or inflammatory measures.
Why it matters
Potential benefit: If successful, combining anti-inflammatory nutrition education with standard non-surgical periodontal care could lower local and systemic inflammation and improve periodontal health.
How similar studies have gone: Some prior research suggests anti-inflammatory diets and nutritional counseling can modestly reduce systemic inflammation and improve periodontal measures, but high-quality trials combining dietary education with periodontal therapy remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being systemically healthy * Not smoking * Not using anti-inflammatory drugs in the last 3 months, antibiotics, or systemic corticosteroids in the last 6 months * Not being pregnant or lactating * Not having received periodontal treatment in the last 6 months * Having at least 20 teeth in the mouth * Being diagnosed with periodontitis by the investigator * Having a dietary inflammatory index \>0 Exclusion Criteria: * Having a systemic disease * Smoking * Using anti-inflammatory drugs within the last 3 months, antibiotics within the last 6 months, or systemic corticosteroids * Being pregnant or lactating * Having received periodontal treatment within the last 6 months * Having fewer than 20 teeth in the mouth * No periodontitis
Where it's running
-
Recep Tayyip Erdoğan University
Rize, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Hatice Yemenoglu
- Email: htcymnglu@hotmail.com
- Phone: +905052977517
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.