Analyzing the impact of dental implant spacing on gum disease risk

Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. A Multi-center Cross-sectional Study

Observational Universitat Internacional de Catalunya · NCT06364982

This study is trying to see if the spacing between dental implants affects the risk of gum disease for people who have had multiple implants placed.

Quick facts

Study typeObservational
Enrollment180 (estimated)
Ages18 Years and up
SexAll
SponsorUniversitat Internacional de Catalunya Academic / other
Locations1 site (Sant Cugat del Vallès, Barcelona)
Trial IDNCT06364982 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the relationship between the distance between contiguous dental implants and the occurrence of peri-implant diseases such as mucositis and peri-implantitis. Conducted as a multicentric cross-sectional study, it follows the STROBE guidelines and involves a stratified random sampling of patients who received at least two contiguous dental implants before 2021. Participants will be contacted for evaluations by trained examiners to assess their peri-implant status based on the inter-implant distances. The study will adhere to ethical standards and obtain informed consent from all participants.

Who should consider this trial

Good fit: Ideal candidates are systemically healthy adults aged 18 and older who have received at least two contiguous dental implants with a minimum of three years of function.

Not a fit: Patients who are pregnant, have taken systemic antibiotics recently, or have undergone treatments that may affect periodontal health will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into optimal dental implant placement to reduce the risk of peri-implant diseases.

How similar studies have performed: While the specific approach of analyzing inter-implant distances is novel, similar studies have explored factors influencing peri-implant health with varying degrees of success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The patient must be ≥18 years of age and systemically healthy;
* Partially edentulous patients, rehabilitated until 2020 (i.e., a minimum of 3 years of function time) with at least two contiguous implant-supported restorations in the maxilla or mandible;
* Screw or cemented-retained prosthesis;
* Fixed dental prosthesis (i.e., single crowns and partial prosthesis);
* No implant mobility.

Exclusion Criteria:

* Pregnant and lactating women;
* Patients who have taken systemic antibiotics during the 3 months prior to the examination;
* Patients being treated with drugs that may induce a gingival overgrowth;
* Patients undergoing orthodontic treatment (since it can influence periodontal diagnosis);
* Patients who have received mechanical debridement during the 3 months prior to the exam;
* Patients who have received surgical treatment for peri-implantitis;
* Psychophysical inability to carry out study procedures.

Where this trial is running

Sant Cugat del Vallès, Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Peri-implant MucositisPeri-ImplantitisPeri-implantitisPeri-implant diseasesPeri-implant mucositisInter-implant distances
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.