Analyzing the effects of fluid bolus treatment in shock patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the haemodynamic effects of administering a standard fluid bolus to patients experiencing shock. It aims to determine the effectiveness of volume expansion through intravenous fluid administration and to identify how much of the fluid administered is actually effective in increasing cardiac output. The study will involve patients aged 18 and older who are hospitalized in intensive care and already have haemodynamic monitoring in place. By analyzing the data collected, the study seeks to provide insights into the optimal management of fluid resuscitation in shock.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years old
* Hospitalisation in intensive care
* Haemodynamic monitoring already in place with a pulse wave contour analysis-derived estimation of cardiac output (either calibrated or uncalibrated)
* Decision taken by the clinicians in charge of the patient to perform volume expansion by intravenous infusion of a 6 mL/kg crystalloid bolus

Exclusion Criteria:

* Pregnancy
* Refusal to participate by relatives of the patient or the patient himself
* Other therapeutic modification during volume expansion

Where it's running

• Bicêtre Hospital
  Le Kremlin-Bicêtre, France Recruiting

Study contacts

• Study coordinator: Xavier Monnet, MD, PhD
• Email: xavier.monnet@aphp.fr
• Phone: +33660862669

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.