Analyzing Herpes Zoster Hospitalizations in Italy

Nationwide Retrospective Observational Study of Herpes Zoster Associated Hospital Admissions in Italy

Observational University of L'Aquila · NCT05952271

This study looks at how often older adults and those with health issues are hospitalized for shingles in Italy and whether there's a link between shingles and COVID-19 to help improve vaccination efforts.

Quick facts

Study typeObservational
Enrollment72000 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorUniversity of L'Aquila Academic / other
Locations1 site (L'Aquila)
Trial IDNCT05952271 on ClinicalTrials.gov

What this trial studies

This observational study aims to describe the incidence of hospital admissions related to Herpes Zoster in Italy, particularly among the elderly and at-risk adults. It focuses on understanding the impact of co-morbidities that may reduce the immune response to the varicella-zoster virus. Additionally, the study will explore the potential relationship between Herpes Zoster and COVID-19 infections. By analyzing hospital discharge records, the study seeks to provide insights that could enhance vaccination uptake and risk perception of the disease.

Who should consider this trial

Good fit: Ideal candidates for this study include adults aged 18 years and older who have been hospitalized for Herpes Zoster.

Not a fit: Patients under 18 years old or those without a Herpes Zoster diagnosis will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved vaccination strategies and reduced hospitalizations for Herpes Zoster.

How similar studies have performed: While there have been studies on Herpes Zoster, this specific observational approach focusing on hospitalization and co-morbidities is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Hospital discharge records for Herpes Zoster infection in primary diagnosis age ≥18 years
* Hospital discharge records for Herpes Zoster infection in secondary diagnoses age ≥18 years

Exclusion Criteria:

* Hospital discharge records for Herpes Zoster infection in primary diagnosis age \<18 years
* Hospital discharge records for Herpes Zoster infection in secondary diagnoses age \<18 years

Where this trial is running

L'Aquila

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Herpes ZosterComorbidities and Coexisting ConditionsVaccinationHospitalizationsComorbidities
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.