Analyzing heart waveforms in patients with persistent atrial fibrillation
A Prospective Randomized Controlled Study on the Waveform Periodicity Analysis of Complex Fractionated Electrograms With OctaRay in Patients With Persistent Atrial Fibrillation
NA · Taipei Veterans General Hospital, Taiwan · NCT06023888
This study is trying to see if a special heart mapping tool can help doctors better understand and treat patients with persistent atrial fibrillation.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Taipei Veterans General Hospital, Taiwan (other gov) |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06023888 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to analyze intracardiac atrial electrogram waveform periodicity in patients suffering from persistent atrial fibrillation. It employs a prospective randomized controlled design using the OCTARAY™ Mapping Catheter to identify critical atrial substrates that contribute to the condition. The study hypothesizes that non-linear electrogram morphology analysis can enhance the understanding of atrial fibrillation sources, potentially leading to improved outcomes in catheter ablation procedures.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with persistent atrial fibrillation who are refractory or intolerant to medication.
Not a fit: Patients who have previously undergone AF ablation or have significant comorbidities such as poor renal function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective catheter ablation techniques for patients with persistent atrial fibrillation.
How similar studies have performed: While the approach of analyzing waveform periodicity is innovative, previous studies have indicated that similar mapping techniques may correlate with better outcomes, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * persistent atrial fibrillation * refractory or intolerant to medication Exclusion Criteria: * Previous AF ablation * LA thrombus * Previous MAZE procedure * Poor renal function * Can't follow-up for one year
Where this trial is running
Taipei
- Taipei Veterans General Hospital — Taipei, Taiwan (RECRUITING)
Study contacts
- Study coordinator: CHIN-YU LIN, DR
- Email: clouaa@gmail.com
- Phone: +886983215656
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Atrial Fibrillation, persistent atrial fibrillation, ablation, driver