Analyzing genetic changes in different types of thyroid cancer
Observational Study Analysing the Transcriptome and Mutational Status of Thyroid Carcinomas of Follicular Origin with Different Degrees of Malignancy
This study is testing how genetic changes in different types of thyroid cancer can help improve diagnosis and treatment for adults with these cancers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Irccs Synlab Sdn Academic / other |
| Locations | 1 site (Naples) |
| Trial ID | NCT06878534 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on thyroid cancers of follicular origin, particularly well-differentiated thyroid carcinomas like papillary and follicular types. It aims to analyze the transcriptome and mutational status of these cancers to understand their varying degrees of malignancy. By examining molecular alterations in key pathways, the study seeks to refine diagnostic criteria and improve treatment strategies for patients with thyroid cancer. The research will involve patients over 18 years old diagnosed with thyroid cancer of follicular origin.
Who should consider this trial
Good fit: Ideal candidates for this study are patients over 18 years old diagnosed with thyroid cancer of follicular origin.
Not a fit: Patients with thyroid cancer types other than follicular origin may not receive benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better diagnostic and treatment approaches for patients with thyroid cancer.
How similar studies have performed: Other studies have shown success in analyzing genetic alterations in thyroid cancers, indicating that this approach is promising.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of either sex aged \> 18 years with thyroid cancer of follicular origin. Exclusion Criteria: * Patients who do not fit the inclusion criteria.
Where this trial is running
Naples
- Irccs Synlab Sdn — Naples, Italy (Recruiting)
Study contacts
- Principal investigator: Giovanni Smaldone — Irccs Synlab Sdn
- Study coordinator: Giovanni Smaldone, Master degree in biothecnology
- Email: giovanni.smaldone@synlab.it
- Phone: +39 0812408294
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.