Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing ELF Test for Early Detection of Fatty Liver in High-Risk Patients

Official title: Exploratory Analysis of Enhanced Liver Function (ELF) Test to Detect Early Fatty Liver in High Risk Population

Run by Methodist Health System · NCT06225193 · Data updated 2026-11-12

This study is testing if a new liver test can help find early signs of fatty liver disease in people at high risk, like those with metabolic syndrome, and see how lifestyle changes or medications affect their liver health over time.

More Fatty Liver trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorMethodist Health System
Academic / other
Locations1 site (Dallas, Texas)
StatusRecruiting
StartedJune 20, 2023
Main results expectedJune 23, 2026
Study endsJune 23, 2026
Registry record updatedMay 13, 2026
Trial IDNCT06225193 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 and older with risk factors for NAFLD/NASH who have undergone ELF score assessment at Methodist Dallas Medical Center.

Probably not a fit

Patients with incomplete data or those lost to follow-up will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze enhanced liver fibrosis (ELF) scores in a high-risk population for nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The study focuses on patients with metabolic syndrome and other risk factors, comparing ELF scores with traditional fibrosis assessment methods. It will also evaluate the impact of lifestyle changes and pharmacotherapy on ELF scores over time. The goal is to provide a non-invasive and cost-effective means of detecting liver fibrosis and predicting liver-related events in primary care settings.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection and better management of fatty liver disease in high-risk patients.

How similar studies have gone: While the ELF test is a newer approach, similar studies have shown promise in using non-invasive methods for liver fibrosis assessment.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: ≥ 18 years
* NAFLD/NASH and non-NAFLD/NASH patients who have had an assessment with ELF score at Methodist Dallas Medical Center from November 2021 to December 2023.

Exclusion Criteria:

* Patients with incomplete data and those lost to follow up.

Where it's running

  • Methodist Dallas Medical Center
    Dallas, Texas, United States
    Recruiting

Study contacts

  • Principal investigator: Parvez Mantry, MD — Methodist Midlothian Medical Center
  • Study coordinator: Crystee Cooper
  • Email: crysteecooper@mhd.com
  • Phone: 2149471280

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.