Analyzing clinical characteristics and diagnostic markers in women with polycystic ovary syndrome
Analysis of Clinical Characteristics and Study of Diagnostic Markers in Patients with Polycystic Ovary Syndrome
This study is trying to find new health markers in women with polycystic ovary syndrome to help create more personalized treatments for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Shanghai 10th People's Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT05063383 on ClinicalTrials.gov |
What this trial studies
This observational study collects clinical data and serum samples from women diagnosed with polycystic ovary syndrome (PCOS) to analyze various health metrics. Using statistical software like SPSS and experimental techniques such as ELISA, the study aims to explore the relationships between body measurements, glucose and lipid metabolism, hormonal levels, and body fat distribution in PCOS patients. The ultimate goal is to identify new biomarkers that could lead to more personalized treatment approaches for women suffering from this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are females aged 18 to 45 who meet the Rotterdam criteria for polycystic ovary syndrome.
Not a fit: Patients who are pregnant, planning pregnancy, or have certain hormonal or metabolic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic markers and personalized treatment options for women with polycystic ovary syndrome.
How similar studies have performed: While this study focuses on specific biomarkers in PCOS, similar observational studies have shown promise in identifying clinical characteristics and improving understanding of the condition.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female aged 18- 45; * Meet Rotterdam criteria; Exclusion Criteria: * Women who are pregnant or have a pregnancy plan within six months; * Congenital adrenocortical hyperplasia; * Hyperprolactinemia; * Hyperthyroidism or hypothyroidism; * Abnormal liver function (≥ 3 times of the upper limit of normal range); * Abnormal renal function (GFR\<60ml/min/1.73m2); * Adrenal or ovarian tumors secreting androgens; * Used contraceptives, metformin, GLP-1RA, pioglitazone and contraceptives in the last 3 month.
Where this trial is running
Shanghai, Shanghai
- Shanghai Tenth People' Hospital — Shanghai, Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Manna Zhang, Dr
- Email: mannazhang@126.com
- Phone: （86）66301004
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.