Analyzing breath compounds in patients with acute chest pain
Application of Emergency Rapid Detection of Expiratory Volatile Organic Compounds (VOCs) in Patients With Acute Cardiogenic Chest Pain
NA · Qilu Hospital of Shandong University · NCT06277895
This study is trying to see if breath samples from people with chest pain can help doctors quickly spot serious heart issues compared to healthy individuals.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 1400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Qilu Hospital of Shandong University (other) |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06277895 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare volatile organic compounds (VOCs) in patients experiencing acute cardiogenic chest pain with those in healthy individuals. It focuses on identifying specific VOC markers that could help in the rapid detection of acute coronary and aortic syndromes. The study will measure VOC levels at baseline and explore the relationship between abnormal VOCs and patient prognosis, particularly concerning early warning signs of acute heart failure.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who are experiencing acute cardiogenic chest pain.
Not a fit: Patients with terminal illnesses or those receiving palliative care may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to a rapid and non-invasive method for diagnosing acute cardiogenic conditions.
How similar studies have performed: While the approach of using VOCs for diagnosis is innovative, similar studies have shown promise in other contexts, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Observation group inclusion criteria: 1. Over 18 years old, male or female; 2. Patients with acute cardiogenic chest pain (see diagnostic criteria); 3. Patient\'s informed consent. Inclusion criteria of healthy control group: 1. Over 18 years old, male or female; 2. Centerless cerebrovascular disease, lung disease, no abnormal liver and kidney function, no acute infection recently; 3. Informed consent. Exclusion Criteria: 1. The patient had difficulty in collecting breath; 2. Patients with terminal illness or receiving palliative care; 3. Have participated in other clinical studies or consider it inappropriate to participate in this study.
Where this trial is running
Jinan, Shandong
- Qilu hospital — Jinan, Shandong, China (RECRUITING)
Study contacts
- Study coordinator: Yuan Bian, Dr.
- Email: bianyuan@sdu.edu.cn
- Phone: +8618560083065
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Coronary Syndrome, Acute Aortic Syndrome