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Clinical trial Recruiting at 1 site Observational Ages 18 to 90

Analyzing brain health indicators in a large cohort

Official title: Clinical Indicators and Brain Image Data: a Cohort Study Based on Kailuan Cohort

Run by Beijing Friendship Hospital · NCT05453877 · Data updated 2026-11-12

This study looks at how medical history and body signals affect brain health and small vessel disease in a large group of people to help find ways to prevent brain problems and improve treatment for those with high blood pressure.

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment1000 (estimated)
SponsorBeijing Friendship Hospital
Academic / other
Locations2 sites (Beijing, Beijing Municipality and 1 other locations)
StatusRecruiting
StartedAugust 1, 2022
Main results expectedAugust 1, 2025
Study endsAugust 1, 2030
Registry record updatedOctober 31, 2022
Trial IDNCT05453877 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 18 to 90 years who have participated in the Kailuan Cohort and have undergone relevant medical assessments.

Probably not a fit

Patients with known congenital or acquired organic diseases, psychiatric disorders, or those who are pregnant or lactating may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between medical history, physiological indicators, and cerebral small vessel disease, along with structural and functional changes in the brain and neck organs. By utilizing a large sample size from the Kailuan Cohort, the study seeks to identify factors influencing the development of these conditions. The findings could provide objective insights for early intervention and improved clinical outcomes for patients with brain diseases and hypertension.

Why it matters

Potential benefit: If successful, this study could lead to better early intervention strategies for cerebral small vessel disease, potentially improving patient outcomes.

How similar studies have gone: While this study builds on existing knowledge, the specific approach of analyzing a large cohort for these particular indicators is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

1. Age from 18 to 90 years old;
2. Comes from the Kailuan Cohort, completed ≥1 visits which the medical history, physiological indicators were measured;
3. Without contraindications of CT and MR scan;
4. Can cooperate with the measurement of the medical history, physiological indicators and brain imaging.

Exclusion Criteria:

1. Known clinical history with congenital or acquired organic diseases (such as aortic stenosis);
2. Known history of drug abuse;
3. Pregnant and lactating women; 4. With clinical history of psychiatric diseases (such as schizophrenia).

Where it's running

  • Kailuan General Hospital
    Tangshan, Hebei, China     Recruiting
  • Beijing Friendship Hospital, Capital Medical University
    Beijing, Beijing Municipality, China     Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.