Analysis of sounds from vascular access in dialysis patients
Official title: Acoustic Analysis of Blood Flow-emitted Sounds to Detect Vascular Complications in Arteriovenous Fistulae and Grafts for Hemodialysis
Run by Mario Negri Institute for Pharmacological Research · NCT05612022 · Data updated 2026-11-12
This study is testing whether listening to the sounds from different types of vascular access can help doctors understand how well they work for patients on dialysis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 44 (estimated) |
| Sponsor | Mario Negri Institute for Pharmacological Research Academic / other |
| Locations | 1 site (Bergamo, BG) |
| Status | Recruiting |
| Started | May 9, 2023 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | November 29, 2024 |
| Trial ID | NCT05612022 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients with end-stage renal disease who are currently on hemodialysis or are entering a pre-dialysis program and require a new vascular access.
✕Probably not a fit
Patients who are using catheters for hemodialysis, undergoing peritoneal dialysis, or have a life expectancy of less than two years may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients with end-stage renal disease (ESRD) who are undergoing hemodialysis and require a new vascular access (VA). It aims to analyze the acoustic properties of sounds generated by arteriovenous fistulas (AVF) and arteriovenous grafts (AVG) to better understand their functionality and potential failure rates. The study will include patients who are either currently on hemodialysis or in a pre-dialysis program, and will assess the effectiveness of different types of vascular access. The goal is to improve the management of vascular access in ESRD patients.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for monitoring and maintaining vascular access in hemodialysis patients, potentially reducing complications and improving patient outcomes.
How similar studies have gone: While the approach of acoustic analysis in vascular access is relatively novel, similar studies have shown promise in improving outcomes for patients with vascular access issues.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Provision of informed consent prior to any study specific procedures. 2. Patients in HD treatment that need a new VA or patients that entered the pre-dialysis program because of ESRD. In all these cases the treatment of first choice should be the creation of a distal autogenous AVF, the creation of an AVG or the proximalization of an occluded VA. Exclusion Criteria: 1. Contraindications for the creation of an autogenous AVF, for the AVG creation or the proximalization of a failed VA. 2. Patients who use catheter to perform HD. 3. Patients undergoing peritoneal dialysis. 4. Patients with life expectancy less than 2 years.
Where it's running
-
ASST HPG23 Unità di Nefrologia e Dialisi
Bergamo, Bg, Italy Recruiting
Study contacts
- Study coordinator: Anna Caroli
- Email: anna.caroli@marionegri.it
- Phone: 003903545351
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Observational study of HeRO Graft and Super HeRO in hemodialysis patients
This study is testing how safe and effective the HeRO Graft System and Super HeRO Adaptor are for adults on hemodialysis who have run out of other options for dialysis access.
-
SelfWrap-Assisted Arteriovenous Fistulas for Chronic Kidney Disease
This study is testing if a new wrap called SelfWrap can make it safer and more effective for people with chronic kidney disease to have a new arteriovenous fistula created.
-
Ribupatide PK in People with Kidney Impairment
This study tests how a single shot of ribupatide behaves in the body for people with severe kidney problems compared to those with normal kidney function.
-
Intradiay dialysis exercise to improve posture in adults with end-stage kidney disease
This study tests whether a 12-week supervised exercise program done during dialysis can improve posture in adults on maintenance hemodialysis.
-
Pumpkin seed oil for people on hemodialysis
This study tests whether taking pumpkin seed oil daily for 3 months helps reduce inflammation and improve-related lab markers in people with end-stage kidney disease on dialysis.
-
Porcine thymokidney transplant for end-stage renal disease
This study tests whether a GalKO porcine thymokidney transplant can keep kidney function without dialysis in adults with end-stage kidney disease who are unlikely to get a standard donor kidney soon.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.