Analysis of chest CT scans from World Trade Center workers

Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates

Icahn School of Medicine at Mount Sinai · NCT03295279

This study looks at chest CT scans from World Trade Center workers to see how their lung health is affected by their work and to understand issues like chronic lung disease and lung cancer.

Quick facts

Study typeObservational
Enrollment2122 (estimated)
Ages18 Years and up
SexAll
SponsorIcahn School of Medicine at Mount Sinai (other)
Locations1 site (New York, New York)
Trial IDNCT03295279 on ClinicalTrials.gov

What this trial studies

This observational study involves the systematic assessment of chest CT scans from World Trade Center workers and volunteers collected between 2003 and 2016. The research team aims to identify findings related to chronic airway disease, interstitial lung disease, and lung cancer, while correlating these findings with clinical and exposure data. The study will also explore the progression of chronic obstructive pulmonary disease (COPD) and the impact of obesity on lung health through advanced imaging techniques and longitudinal data analysis.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who participated in the WTC Health Plan Clinical Center Excellence program and have undergone chest CT imaging.

Not a fit: Patients who are not part of the WTC Health Plan or do not have relevant lung conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of lung diseases related to World Trade Center exposure and improve monitoring and treatment strategies for affected individuals.

How similar studies have performed: Other studies focusing on the health impacts of the World Trade Center disaster have shown promising results, indicating that this approach is built on established research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All subjects will be participants in the screening/monitoring (SMP) and treatment program (TP) sides of the WTC Health Plan Clinical Center Excellence at Mount Sinai Medical Center, the major site, by far of the NY/NJ consortium of this program.

Exclusion Criteria:

* Special vulnerable populations, such as fetuses, neonates, pregnant women, children, prisoners, institutionalized individuals, will not be involved in this research study.

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Chronic Airway Disease, Interstitial Lung Disease, Lung Cancer, World Trade Center, Quantitative computerized tomography, Qualitative computerized tomography of the chest, Chronic airway disease, Interstitial lung disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.