Amino acid supplementation for patients undergoing kidney dialysis
Amino Acid Supplementation in Continuous Renal Replacement Therapy
This study tests if giving extra amino acids to patients on kidney dialysis can improve their health while they are in the ICU.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Karolinska University Hospital Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT06835816 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of amino acid supplementation in patients receiving continuous renal replacement therapy (CRRT) for acute kidney injury. Patients will have blood samples drawn before and after the initiation of amino acid supplementation, which will be administered in increasing doses over a period of 20-24 hours. The study aims to assess the impact of this supplementation on patient outcomes during CRRT. The approach focuses on optimizing nutritional support for critically ill patients in the ICU.
Who should consider this trial
Good fit: Ideal candidates for this study are ICU patients who are scheduled to receive continuous renal replacement therapy and require amino acid supplementation.
Not a fit: Patients with liver failure, muscle disease, or neurodegenerative disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve recovery outcomes for patients with acute kidney injury undergoing dialysis.
How similar studies have performed: While there may be limited data on this specific approach, similar studies exploring nutritional supplementation in critically ill patients have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dialysis where amino acid supplementation is planned by treating physician Exclusion Criteria: * Liver failure * Muscle disease * Neurodegenerative disease
Where this trial is running
Stockholm
- Karolinska University Hospital — Stockholm, Sweden (Recruiting)
Study contacts
- Principal investigator: Jonathan Grip, MD, PhD — Karolinska University Hospital
- Study coordinator: Jonathan Grip, MD, PhD
- Email: jonathan.grip@regionstockholm.se
- Phone: +46736230906
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.