Amino acid supplementation for patients undergoing kidney dialysis
Official title: Amino Acid Supplementation in Continuous Renal Replacement Therapy
Run by Karolinska University Hospital · NCT06835816 · Data updated 2026-11-12
This study tests if giving extra amino acids to patients on kidney dialysis can improve their health while they are in the ICU.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Karolinska University Hospital Academic / other |
| Locations | 1 site (Stockholm) |
| Status | Recruiting |
| Started | February 3, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2028 |
| Registry record updated | February 19, 2025 |
| Trial ID | NCT06835816 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are ICU patients who are scheduled to receive continuous renal replacement therapy and require amino acid supplementation.
✕Probably not a fit
Patients with liver failure, muscle disease, or neurodegenerative disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of amino acid supplementation in patients receiving continuous renal replacement therapy (CRRT) for acute kidney injury. Patients will have blood samples drawn before and after the initiation of amino acid supplementation, which will be administered in increasing doses over a period of 20-24 hours. The study aims to assess the impact of this supplementation on patient outcomes during CRRT. The approach focuses on optimizing nutritional support for critically ill patients in the ICU.
Why it matters
Potential benefit: If successful, this study could improve recovery outcomes for patients with acute kidney injury undergoing dialysis.
How similar studies have gone: While there may be limited data on this specific approach, similar studies exploring nutritional supplementation in critically ill patients have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dialysis where amino acid supplementation is planned by treating physician Exclusion Criteria: * Liver failure * Muscle disease * Neurodegenerative disease
Where it's running
-
Karolinska University Hospital
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: Jonathan Grip, MD, PhD — Karolinska University Hospital
- Study coordinator: Jonathan Grip, MD, PhD
- Email: jonathan.grip@regionstockholm.se
- Phone: +46736230906
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.