American ginseng's effects on urine and blood metabolites
Official title: LCMS-Based Metabolic Analysis Explores the Effect of American Ginseng on Urine and Plasma in Healthy Individuals
Run by Zhejiang Cancer Hospital · NCT07252362 · Data updated 2026-11-12
This test will see if taking 3 grams of American ginseng daily for 14 days changes metabolites in urine and blood in healthy adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | Zhejiang Cancer Hospital Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Status | Recruiting |
| Started | November 11, 2023 |
| Main results expected | December 30, 2025 |
| Study ends | March 30, 2026 |
| Registry record updated | November 26, 2025 |
| Trial ID | NCT07252362 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy adults aged 18–45 with no major medical history, normal routine physical exam results, no known drug allergies, and willingness to follow dietary restrictions and attend fasting sample visits.
✕Probably not a fit
People with chronic illnesses, current medication use, known drug allergies, or those outside the 18–45 age range are unlikely to benefit or qualify for this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will give healthy adults 3 grams of American ginseng powder daily for 14 days and use LC‑MS metabolomic analysis to profile changes in urine and plasma. Fasting urine samples will be collected at baseline, day 7, and day 14, and fasting serum samples at baseline and day 14 at Zhejiang Cancer Hospital. Participants will follow a light diet, avoid alcohol and caffeine, and be monitored for any adverse effects throughout the study. The trial enrolls healthy volunteers aged 18 to 45 with no significant medical history or drug allergies.
Why it matters
Potential benefit: If successful, this could reveal how American ginseng alters metabolism and identify biomarkers to guide safe use or future therapeutic research.
How similar studies have gone: Previous metabolomics studies of botanical supplements and some work on American ginseng have shown metabolic changes, but LC‑MS profiling in healthy volunteers for this specific question is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
* 18 to 45 years old; * The subjects were fully informed about the research process and signed the informed consent form (the subjects had no abnormalities in routine physical examinations, no previous medical history, and no history of drug allergies); ③ During the trial, they were required to have a light diet and were prohibited from consuming alcoholic and caffeinated beverages;
Where it's running
-
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, China Recruiting
Study contacts
- Study coordinator: guan ai Bao, Master
- Email: doctorbga@126.com
- Phone: +8615968857341
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.