Alternate Nostril Breathing vs Diaphragmatic Breathing after PCI
Official title: Effects of Alternate Nostril Breathing Versus Diaphragmatic Breathing on Oxygen Saturation and Heart-rate Variability in Post Percutaneous Coronary Intervention Patients
Run by Foundation University Islamabad · NCT07867457 · Data updated 2026-11-12
Post-PCI patients will try two breathing techniques to see which helps keep oxygen levels steady and heart-rate variability better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 44 Years to 75 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Foundation University Islamabad Academic / other |
| Locations | 1 site (Rawalpindi) |
| Status | Recruiting |
| Started | February 11, 2026 |
| Main results expected | December 15, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | October 9, 2026 |
| Trial ID | NCT07867457 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 44-75 who are hemodynamically stable after PCI and can follow simple breathing instructions.
✕Probably not a fit
Patients with ongoing ischemia, instability, or contraindications to deep breathing may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, parallel-group study compares alternate nostril breathing to diaphragmatic breathing in hemodynamically stable patients after percutaneous coronary intervention. Participants are randomly assigned 1:1 and receive the assigned breathing exercise for two consecutive days with three supervised sessions per day, in addition to routine post-PCI care. Outcomes include oxygen saturation and heart-rate variability measured at baseline and after the intervention using pulse oximetry and a heart-rate monitor. Safety monitoring includes vitals during sessions, with stopping rules for adverse signs. Conducted at Foundation University Islamabad, Rawalpindi, the trial aims to determine if one breathing approach more favorably influences autonomic and oxygen metrics in this population.
Why it matters
Potential benefit: If successful, a simple breathing technique could help stabilize oxygen levels and autonomic function after PCI.
How similar studies have gone: Prior research in breathing techniques for cardiac patients shows variable effects; this study explores a direct post-PCI context with objective physiological outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 44-75 years * Hemodynamically stable post-PCI patients with systolic blood pressure\>90 mmHg, diastolic BP 50-100mmHg Heart-rate 60-100 beats/min and no ongoing chest pain or signs of acute clinical instability. * Oxygen saturation \>92% on room air * Able to follow simple verbal instructions and perform the breathing exercises. * Ejection Fraction \>35% Exclusion Criteria: * Ongoing myocardial ischemia, unstable angina, significant arrythmia or requirement for inotropic/vasopressor support. * Cardiogenic shock or severe heart failure (NYHA class IV) * Recent thoracic surgery or chest wall injury limiting rib expansion or deep breathing. * Cardiac implantable electronic device (pacemaker/ICD) with pacing dependency or an implanted ventricular assist device. * Severe cognitive impairment * Uncontrolled hypertension(SBP\>180 mmHg or DBP\>110 mmHg) or bradycardia\<50 beats/min. * Severe anemia (Hb\<8g/dL)
Where it's running
-
Foundation University Islamabad
Rawalpindi, Pakistan Recruiting
Study contacts
- Study coordinator: Sonia Jahangir, MS-CPPT
- Email: Soniajahangir23@gmail.com
- Phone: 0340-6801014
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Validation of a device for monitoring vital signs in children
This study is testing a new device called the VT-Patch® to see if it accurately measures vital signs like heart rate and temperature in children with different skin colors.
-
Impact of Kangaroo Care on Weight Gain in Preterm Infants
This study is testing if holding preterm infants skin-to-skin during their first feeding helps them gain weight better than if they are held during their second feeding.
-
Pilates breathing vs diaphragmatic breathing after PCI
This study tests whether Pilates breathing or diaphragmatic breathing helps improve oxygen levels and heart-rate variability in people who just had PCI.
-
Breathing retraining for pregnant women with POTS
This trial will test whether diaphragmatic breathing exercises help pregnant women with POTS reduce dizziness, rapid heart rate, and other orthostatic symptoms.
-
Think Tank nutritional drink to help thinking after stress in middle-aged women.
This trial will test whether taking the 'Think Tank' nutritional drink helps thinking and mood after a physical and psychological stressor in healthy women aged 40–60 who drink caffeine daily.
-
Nellcor Device Sitting-Walking Test for Pulse Oximetry
This study tests how accurately the Nellcor device measures heart rate and blood oxygen levels when people are resting and walking.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.