Alb-PRF vs PRF to reduce pain and improve healing after palate graft harvesting

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial will enroll 39 adult participants at Cairo University and follow them for 28 days after free gingival graft (FGG) harvesting. Participants will be randomly assigned to one of three groups: Alb-PRF applied to the palatal donor site, PRF applied to the donor site, or an absorbable gelatin sponge as control. Procedures include standard FGG harvesting under local anesthesia and preparation of autologous blood products from a 10 ml venous draw. Outcomes focus on postoperative morbidity at the donor site including pain, bleeding, and wound healing over the one-month follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients in need of free gingival graft
2. Medically free patients
3. Adult patients above 18 years old.
4. Patients accepting a 1-month follow-up period (cooperative patients).
5. Patients who will provide an informed consent.

Exclusion Criteria:

1. Smokers
2. Pregnant and lactating women
3. Patients with poor oral hygiene
4. Patients who had previous periodontal surgery in the area of interest

Where it's running

• Cairo University
  Cairo, Cairo Governorate, Egypt Recruiting
• Cairo University
  Giza, Cairo Governorate, Egypt Recruiting
• Cairo University
  Cairo, Cairo Governorate, Egypt Not yet recruiting

Study contacts

• Study coordinator: Samar Idris Hamadelnil Idris Samar Idris, master
• Email: samar.Idris@dentistry.cu.edu.eg
• Phone: 01273600331

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.