Airway clearance techniques for bronchiectasis

Efficacy and Safety of Airway Clearance Technique by Oscillation and Lung Expansion in Patients With Bronchiectasis

NA · Shanghai Pulmonary Hospital, Shanghai, China · NCT06393257

This study tests a new airway clearance technique to see if it helps people with bronchiectasis feel better and clear mucus more effectively than the traditional method.

Quick facts

PhaseNA
Study typeInterventional
Enrollment96 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorShanghai Pulmonary Hospital, Shanghai, China (other)
Locations3 sites (Shanghai, Shanghai Municipality and 2 other locations)
Trial IDNCT06393257 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness and safety of an airway clearance technique called Oscillation and Lung Expansion in patients with bronchiectasis. Participants will be randomly assigned to receive either this new technique or traditional postural drainage. The study aims to compare symptom relief, quality of life, and the amount of mucus expectorated between the two groups. By evaluating these outcomes, the trial seeks to determine the superior method for managing bronchiectasis exacerbations.

Who should consider this trial

Good fit: Ideal candidates for this study are adults experiencing acute exacerbations of bronchiectasis.

Not a fit: Patients with severe complications such as significant haemoptysis or recent lung surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective airway clearance method for patients with bronchiectasis, improving their quality of life.

How similar studies have performed: While similar airway clearance techniques have been explored, this specific approach is novel and has not been extensively tested in bronchiectasis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with acute exacerbation of bronchiectasis

Exclusion Criteria:

* Haemoptysis greater than 50ml
* state of endangerment
* pneumothorax
* Lung surgery history within 6 months
* Severe heart, brain and nervous system diseases

Where this trial is running

Shanghai, Shanghai Municipality and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Bronchiectasis Adult, bronchiectasis, Airway Clearance Technique

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.