AI reading of ECGs to find occlusion myocardial infarction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults presenting with symptoms of acute coronary syndrome but without clear ST-elevation are randomized 1:1 to have their ECG interpreted with an AI tool (PMcardio) or to standard care. The study compares time to coronary intervention and infarct size, with infarct size measured by peak high-sensitivity troponin T (hsTnT). Key eligibility includes age 18+, symptom onset within 24 hours, and ability to give informed consent, while patients with a clear STEMI diagnosis, pregnancy/lactation, or legal incapacity are excluded. The trial is conducted at Cardiocentro Ticino in Lugano and focuses on care timelines and biomarker outcomes between the two arms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Symptoms suspected of ongoing acute myocardial ischemia: Patients presenting with symptoms such as chest pain, dyspnoea, sweating, nausea or vomiting, pain radiating to the shoulder/arm/jaw/back, fatigue, or light-headedness
2. Age: Patients aged 18 years or older.
3. Informed Consent: Patients able to provide informed consent

Exclusion Criteria:

1. Clear diagnosis of ST-segment elevation MI (STEMI) according to managing physicians.
2. Pregnancy or Lactation.
3. Legally incompetent to provide informed consent.
4. Symptoms onset\>24 hrs prior to clinical presentation.

Where it's running

• Cardiocentro Ticino Institute
  Lugano, Canton Ticino, Switzerland Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.