AI-guided cognitive behavioral therapy for depression and anxiety

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This controlled clinical trial will compare an AI-guided cognitive behavioral therapy program delivered via a digital platform with standard psychiatric care in adults with mild depressive and/or anxiety disorders. Eligible participants recruited from outpatient services at the University Clinical Center Niš will be allocated to either the AI-guided CBT arm or a control arm receiving usual care. The intervention consists of weekly 45–60 minute structured sessions over 10 weeks, delivered through the digital platform with clinician supervision. Outcomes will be measured at baseline, mid-treatment (5 weeks), and post-treatment (10 weeks).

Why it matters

Who can join: the full rules

Inclusion Criteria:

Age 18 years or older Diagnosis of mild depressive disorder and/or anxiety disorder confirmed by a structured clinical interview (MINI) Ability to understand and provide informed consent Access to a device capable of using the digital platform (computer, tablet, or smartphone) Willingness to participate in weekly sessions over a 10-week period

Exclusion Criteria:

Moderate to severe depressive disorder Current or past diagnosis of psychotic disorder Bipolar disorder Substance use disorder or dependence Primary diagnosis of antisocial personality disorder Severe cognitive impairment or inability to use digital tools Acute suicidal risk requiring immediate intervention Concurrent participation in another structured psychotherapy program-

Where it's running

• University Clinical Center Niš
  Niš, Serbia Recruiting

Study contacts

• Study coordinator: Aleksandra Stojanovic, MD, PhD Candidate
• Email: drakiwatson@gmail.com
• Phone: +381642293541

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.