Clinical trial Recruiting at 1 site Interventional Ages 65 and up

AI-based e-consults: how patients and clinicians choose between human and AI advice in primary care

Official title: Evaluating the Safety and Appropriateness of AI-based E-Consults for Older Adults in Primary Care

Run by University of Pennsylvania · NCT07766694 · Data updated 2026-11-12

Older adults and primary care clinicians will compare human versus AI-generated e-consults to see which factors—who gives the advice, wait time, cost, and quality—matter most when deciding which to use.

Quick facts

Study typeInterventional
Ages65 Years and up
SexAll
Enrollment220 (estimated)
SponsorUniversity of Pennsylvania
Academic / other
Locations1 site (Philadelphia, Pennsylvania)
StatusRecruiting
StartedSeptember 3, 2026
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedSeptember 9, 2026
Trial IDNCT07766694 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal participants are adults 65+ who have recent Penn Medicine primary care visits and upcoming appointments, and Penn Medicine clinicians (physicians, NPs, PAs) in primary care.

Probably not a fit

Patients with dementia or those outside the Penn Medicine system may be less likely to benefit from findings about AI-based e-consults in this setting.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study uses a discrete choice experiment to explore preferences for electronic consultations in primary care. Participants will complete a one-time survey that presents pairs of hypothetical e-consults differing in provider type (human vs AI), wait time, cost, and quality. The goal is to understand how older patients and clinicians weigh tradeoffs when considering AI-assisted e-consults. The setting is Penn Medicine, with both patients aged 65+ and primary care clinicians participating.

Why it matters

Potential benefit: If successful, findings could guide how e-consults are designed and communicated to align with patient and clinician preferences, potentially improving acceptance and use of AI-assisted guidance.

How similar studies have gone: Previous studies in AI-advised clinical tools have shown mixed acceptance; this study adds targeted insights for elderly patients and primary care clinicians.

Who can join: the full rules

Show full inclusion / exclusion criteria
PATIENTS:

Inclusion Criteria:

* Adult, 65 years of age or older
* Had at least two office visits at Penn Medicine in the past 12 months
* Has an upcoming appointment in a Penn Medicine primary care setting, including family medicine, internal medicine, and geriatric medicine

Exclusion Criteria:

* Documented Alzheimer's, dementia, or related condition

CLINICIANS:

Inclusion Criteria:

* Adult, 18 years of age or older
* Works at Penn Medicine as one of the following: physician, nurse practitioner, or physician's assistant
* Works in a primary care Penn Medicine setting including: family medicine, internal medicine, geriatrics medicine

Exclusion Criteria:

* Actively in medical school, internship, or residency

Where it's running

  • University of Pennsylvania
    Philadelphia, Pennsylvania, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.