AI-assisted sperm selection for infertility treatment
SprmPik AI Assisted Sperm Selection Study, an Assistant for Sperm Selection During ICSI
This study is testing if a new AI software can help choose better sperm for fertility treatments to improve pregnancy success rates.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 155 (estimated) |
| Sex | All |
| Sponsor | Ovation Fertility Academic / other |
| Locations | 2 sites (Las Vegas, Nevada and 1 other locations) |
| Trial ID | NCT06518928 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of the SiD software, which uses artificial intelligence to assist in selecting sperm for intracytoplasmic sperm injection (ICSI) in medically assisted reproduction. The research focuses on measuring outcomes such as fertilization rates, blastocyst formation, and early pregnancy loss. By employing a mathematical model, SiD aims to enhance the traditional sperm selection process performed by embryologists, potentially leading to improved clinical outcomes in fertility treatments.
Who should consider this trial
Good fit: Ideal candidates include couples undergoing ICSI with a male partner providing motile sperm and a female partner with at least four mature oocytes.
Not a fit: Patients with immotile sperm or those requiring sperm extraction via testicular biopsy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve fertilization and pregnancy rates for couples facing infertility.
How similar studies have performed: While the use of AI in sperm selection is a novel approach, similar studies have shown promising results in improving assisted reproductive technologies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria for Male Partner (sperm source) * Informed consent signed by the patient before treatment. * IVF treatments with medical or embryology indication to perform ICSI. * Fresh or frozen ejaculated motile sperm. * Selection of sperm using a 7% or 10% PVP solution. * Presence of motile sperm at the time of sperm selection for ICSI. * Partner sperm Exclusion criteria for Male Partner (sperm source) * Sperm extracted by testicular biopsy. * That the recommendations for use of SiD have not been fully followed. * Inability to reliably trace sperm-oocyte-embryo throughout the process. * Patients with immotile sperm Inclusion criteria for Female Partner (egg source) * Informed consent signed by the patient before treatment. * IVF treatments with medical or embryology indication to perform ICSI. * Cycles with at least 4 mature oocytes (Metaphase II). * Fresh or frozen oocytes. Exclusion criteria for Female Partner (egg source) * Inability to reliably trace sperm-oocyte-embryo throughout the process. * Oocytes that are not in Metaphase II.
Where this trial is running
Las Vegas, Nevada and 1 other locations
- Ovation Fertility Las Vegas — Las Vegas, Nevada, United States (Recruiting)
- Ovation Fertility - Austin — Austin, Texas, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.