AH Plus Jet Root Canal Sealer: Testing a Modified Formula versus Original in Single-Cone Treatments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants with one or two planned primary root canal treatments on anterior teeth or premolars are randomly assigned to receive either the modified AH Plus Jet sealer or the original material using a single-cone technique. The study is a prospective, parallel-group, randomized, post-market clinical follow-up designed to compare performance and safety over 24 months. The analysis treats each tooth as an independent unit, with up to two teeth per participant. Follow-up visits assess outcomes related to sealant performance and any adverse events.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adult aged 18-75 at time of informed consent.
2. Subject willing to participate in the clinical investigation and able to understand the content of the clinical investigation.
3. Subject willing to return for follow-up visits.
4. Subject has signed and dated the informed consent form.
5. Subject in need of one or two primary root canal treatment on mature permanent anterior (incisor or canine) or premolar tooth.
6. Planned study tooth has a favorable prognosis for the next 2 years.

Exclusion Criteria:

1. History of allergic reaction to epoxy resins or amines or any of the other product components.
2. Subject has significant systemic health issues or chronic conditions (American Society of Anesthesiologists (ASA) class 3-6).
3. Known pregnancy or is breastfeeding at time of enrolment or at the RCT visit.
4. Subject unlikely to comply with investigational procedures, as judged by the Investigator.
5. Sign of sinus tract or gingival swelling in the planned study position.
6. Previous enrolment in the present clinical investigation.
7. Involvement in the planning and conduct of the clinical investigation (applies to both Dentsply Sirona personnel and the clinical investigation site).
8. Participation in another clinical investigation that may interfere with the present clinical investigation.
9. Subject experiencing an intraoperative condition that may interfere with the evaluation of the investigational root canal sealer.

Where it's running

• New York University College of Dentistry
  New York, New York, United States Recruiting

Study contacts

• Study coordinator: Mikaela Friberg
• Email: mikaela.friberg@dentsplysirona.com
• Phone: +46 702 644 357

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• 3D-printed versus milled complete dentures in adults who are fully denture dependent

  This study tests whether 3D-printed dentures stay in place and perform as well as milled dentures over five years in adults who need full upper and/or lower dentures.

  Recruiting Dentsply Sirona Implants and Consumables · Chapel Hill, North Carolina · NCT07586774

• Comparing scalloped, straight, and straight-extended trimlines for SureSmile clear aligners

  This study tests whether three different trimline designs for SureSmile clear aligners give accurate tooth movements in adults with mild-to-moderate malocclusion.

  Recruiting at 3 sites Dentsply Sirona Implants and Consumables · Fresno, California and 5 other locations · NCT07290790

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.