Clinical trial Recruiting at 1 site Interventional Ages 12 to 17

After-school program to improve cultural identity and prevent substance use in American Indian youth

Official title: Native Spirit: Culturally-grounded Substance Use Prevention for Indigenous Adolescents

Run by Arizona State University · NCT06785311 · Data updated 2026-11-12

This study tests whether an after-school program can help American Indian teens feel more connected to their culture and reduce substance use.

Quick facts

Study typeInterventional
Ages12 Years to 17 Years
SexAll
Enrollment60 (estimated)
SponsorArizona State University
Academic / other
Locations2 sites (Scottsdale, Arizona and 1 other locations)
StatusRecruiting
StartedJanuary 9, 2025
Main results expectedDecember 31, 2026
Study endsAugust 31, 2027
Registry record updatedFebruary 17, 2026
Trial IDNCT06785311 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English-speaking adolescents in grades 7-12 who are members of the Salt River Pima Maricopa Indian Community or the Pascua Yaqui Tribe.

Probably not a fit

Non-American Indian adolescents will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to adapt, implement, and evaluate the Native Spirit after-school program within urban American Indian communities. The program focuses on enhancing cultural identity, self-esteem, and resilience among adolescents in grades 7-12 while preventing substance use. Utilizing community-based participatory research methods, the study will involve local community members and tribal partners to ensure cultural relevance and engagement. Participants will undergo a baseline assessment followed by a 10-session intervention designed to increase exposure to local cultural values and activities.

Why it matters

Potential benefit: If successful, this program could significantly reduce substance use and improve mental health outcomes among American Indian youth.

How similar studies have gone: Previous studies have shown success with culturally-specific after-school programs in improving health outcomes among American Indian youth, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion:

* English-speaking
* Currently in grade 7-12 at time of enrollment
* Member of the Salt River Pima Maricopa Indian Community (SRPMIC) OR member of the Pascua Yaqui Tribe (PYT)
* Engaged in after school programs.

Exclusion:

• Non-American Indians will be excluded from statistical analysis

Where it's running

  • Way of Life Facility
    Scottsdale, Arizona, United States
    Recruiting
  • Pascua Yaqui Tribe Boys & Girls Club
    Tucson, Arizona, United States
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.