Aerobic exercise program for people with opioid use disorder
The Potential of Exercise to Reduce Pain and Enhance Mobility in Mid-life Adults Undergoing Opioid Use Treatment
This study tests whether a 12-week supervised exercise program can help people with opioid use disorder improve their health and well-being.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 21 Years to 64 Years |
| Sex | All |
| Sponsor | University of Florida Academic / other |
| Locations | 1 site (Gainesville, Florida) |
| Trial ID | NCT05772884 on ClinicalTrials.gov |
What this trial studies
This study examines the effectiveness of a supervised aerobic exercise program specifically designed for individuals with Opioid Use Disorder (OUD). Participants will undergo a 12-week intervention that includes screening, baseline assessments, and regular exercise sessions. The goal is to evaluate the feasibility and acceptability of this exercise regimen in improving health outcomes for this population. The study will be conducted at the University of Florida, where participants will be closely monitored throughout the program.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21-64 who are currently enrolled in opioid maintenance treatment and are insufficiently physically active.
Not a fit: Patients with uncontrolled major psychiatric conditions or significant cardiovascular issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could improve physical health and overall well-being for patients struggling with opioid use disorder.
How similar studies have performed: Other studies have shown positive outcomes with exercise interventions for substance use disorders, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults must be aged 21-64 years old * Currently enrolled in OMT (opioid maintenance treatment) or present with at least mild opioid use disorder (endorses at least 2 DSM-V criteria for OUD within a 12-month period), * Insufficiently physically active (defined as exercising \< 20 minutes 3 times/week * Able to understand and speak English * Have a body mass index 18.5-40 kg/m\^2 * Willing and able to visit research center up to one time time/week for 12 weeks * Participants will undergo a supervised maximal exercise test and physical exam by medical supervisor to be cleared for participation. Exclusion Criteria: * Participants must not have heart disease, or had a stroke, uncontrolled diabetes, thyroid condition an eating disorder * An uncontrolled major psychiatric condition (e.g., schizophrenia; conditions that are well-controlled, however \[e.g., anxiety controlled through therapy\] will not be exclusionary), or other medical condition(s) that contraindicate exercise; and may not be participating in a structured exercise training or weight loss program. * Participants cannot be pregnant; pregnancy is exclusionary * One individual per household may enroll.
Where this trial is running
Gainesville, Florida
- University of Florida — Gainesville, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Meredith S Berry, PhD — University of Florida
- Study coordinator: Lauren E Nieder, MSPH
- Email: lauren.nieder@ufl.edu
- Phone: (352) 294-1067
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.